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RiSE Internship - Translatable In Vitro Drug Discovery for Duchenne Muscular Dystrophy (DMD) (12 months)(m/w/x)

Basel
Full-timeInternshipOn-site

Maintaining 3D tissue cultures and designing pharmacological assays for Duchenne Muscular Dystrophy research. Advanced cell culturing and in vitro electrophysiology skills required. Guidance from Roche scientists, worldwide RiSE Alumni network.

Requirements

  • Master's program graduation within last year or enrolled PhD/medical degree program
  • Culturing complex cell models/organoids
  • In vitro electrophysiology
  • In vitro live cell techniques/assays
  • Familiarity with advanced image analysis software
  • Basic molecular biology techniques
  • Proficiency in statistical software for biological data analysis
  • Strong interest in expanding muscle biology skills
  • Non-EU/EFTA citizens: PhD/medical degree, mandatory industry internship certificate

Tasks

  • Maintain 2D and 3D tissue cultures
  • Plan and design pharmacological assays
  • Perform and analyze small molecule treatments
  • Assess reporter expression and cellular bioenergetics
  • Conduct 3D twitch and tetanic force assessments
  • Record live imaging and contractility of 3D organoids
  • Work closely with a team of scientists and students
  • Coordinate with internal core facilities
  • Collaborate with cross-functional teams
  • Maintain detailed electronic lab notebook
  • Present research findings at internal meetings
  • Summarize work and draft scientific manuscript

Education

  • Master's degree

Languages

  • EnglishBusiness Fluent

Tools & Technologies

  • Mantarray
  • Agilent Seahorse
  • Harmony
  • FIJI/ImageJ
  • MuscleMotion
  • Pulse
  • R
  • GraphPad

Benefits

Mentorship & Coaching

  • Comprehensive guidance from Roche scientists

Startup Environment

  • Worldwide network of RiSE Alumni
Find the original job posting in its most current version here. Nejo automatically captured this job from the website of Roche and processed the information on Nejo with the help of AI for you. Despite careful analysis, some information may be incomplete or inaccurate. Please always verify all details in the original posting! Content and copyrights of the original posting belong to the advertising company.

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