Roche
RiSE Internship - Establishing a reliable human inducible oligodendrocyte precursor cell iPSC protocol for the purpose of high throughput phenotypic analysis(m/w/x)
Full-timeInternshipOn-site
Basel
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F.F. Hoffmann-La Roche AG
RiSE Internship - Identifying Novel Therapeutic Targets for Progressive Multiple Sclerosis(m/w/x)
Basel
Full-timeInternshipOn-site
Nejo AI Summary
Multiplex immunofluorescence and spatial proteomics on human MS tissue, with laser-capture microdissection. 'Omic' data generation and quantitative image analysis using HALO or Visiopharm platforms required. Industry internship experience, neurobiology or neuropathology background, and lab skills in histology, cell culture, and biochemical assays needed.
Requirements
- Graduated within the last year or enrolled in PhD/medical program
- Seeking industry internship experience
- Experience in cellular neurobiology, neuroimmunology, or neuropathology
- Lab experience in histology, cell culture, and biochemical assays
- Interest in iPSC-derived microglia and digital pathology platforms or spatial omics
- Independent, proactive, collaborative, high data documentation standards
- Non-EU/EFTA citizens: PhD/medical program enrollment with mandatory internship certificate
Tasks
- Use automated multiplex immunofluorescence and spatial proteomics on human MS tissue
- Execute laser-capture microdissection (LCM) on MS lesions
- Generate high-quality 'omic' data for target identification
- Perform whole slide scanning and quantitative image analysis
- Use platforms like HALO or Visiopharm for image analysis
- Culture and differentiate human induced pluripotent stem cells (iPSCs)
- Conduct functional in vitro assays using human iPSC-derived microglia
- Evaluate impact of pharmacological agents on iron sequestration and neurotoxicity
- Present progress at internal meetings
- Contribute to manuscript preparation for peer-reviewed journal
- Receive mentorship from two Roche scientists
- Collaborate with in vitro and tissue labs
Education
- Currently in higher educationOR
- Bachelor's degree
Languages
- English – Business Fluent
Tools & Technologies
- HALO
- Visiopharm
Find the original job posting in its most current version here. Nejo automatically captured this job from the website of F. Hoffmann-La Roche AG and processed the information on Nejo with the help of AI for you. Despite careful analysis, some information may be incomplete or inaccurate. Please always verify all details in the original posting! Content and copyrights of the original posting belong to the advertising company.
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F.F. Hoffmann-La Roche AG
RiSE Internship - Identifying Novel Therapeutic Targets for Progressive Multiple Sclerosis(m/w/x)
Basel
Full-timeInternshipOn-site
Nejo AI Summary
Multiplex immunofluorescence and spatial proteomics on human MS tissue, with laser-capture microdissection. 'Omic' data generation and quantitative image analysis using HALO or Visiopharm platforms required. Industry internship experience, neurobiology or neuropathology background, and lab skills in histology, cell culture, and biochemical assays needed.
Requirements
- Graduated within the last year or enrolled in PhD/medical program
- Seeking industry internship experience
- Experience in cellular neurobiology, neuroimmunology, or neuropathology
- Lab experience in histology, cell culture, and biochemical assays
- Interest in iPSC-derived microglia and digital pathology platforms or spatial omics
- Independent, proactive, collaborative, high data documentation standards
- Non-EU/EFTA citizens: PhD/medical program enrollment with mandatory internship certificate
Tasks
- Use automated multiplex immunofluorescence and spatial proteomics on human MS tissue
- Execute laser-capture microdissection (LCM) on MS lesions
- Generate high-quality 'omic' data for target identification
- Perform whole slide scanning and quantitative image analysis
- Use platforms like HALO or Visiopharm for image analysis
- Culture and differentiate human induced pluripotent stem cells (iPSCs)
- Conduct functional in vitro assays using human iPSC-derived microglia
- Evaluate impact of pharmacological agents on iron sequestration and neurotoxicity
- Present progress at internal meetings
- Contribute to manuscript preparation for peer-reviewed journal
- Receive mentorship from two Roche scientists
- Collaborate with in vitro and tissue labs
Education
- Currently in higher educationOR
- Bachelor's degree
Languages
- English – Business Fluent
Tools & Technologies
- HALO
- Visiopharm
Find the original job posting in its most current version here. Nejo automatically captured this job from the website of F. Hoffmann-La Roche AG and processed the information on Nejo with the help of AI for you. Despite careful analysis, some information may be incomplete or inaccurate. Please always verify all details in the original posting! Content and copyrights of the original posting belong to the advertising company.
About the Company
F. Hoffmann-La Roche AG
Industry
Pharmaceuticals
Description
Das Unternehmen ist ein führender Anbieter von pharmazeutischen Wirkstoffen und setzt sich für die Gesundheitsversorgung weltweit ein.
Not a perfect match?
- Roche
RiSE Internship - Establishing a reliable human inducible oligodendrocyte precursor cell iPSC protocol for the purpose of high throughput phenotypic analysis(m/w/x)
Full-timeInternshipOn-siteBasel - F. Hoffmann-La Roche AG
RiSE Internship - Targeting CNS Meninges(m/w/x)
Full-timeInternshipOn-siteBasel - 1201 F. Hoffmann-La Roche AG
PhD Internship in Neuromuscular Disorders Lab for 12 months - RiSE(m/w/x)
Full-timeInternshipOn-siteBasel - 1201 F. Hoffmann-La Roche AG
PhD Internship / RiSE - Functional characterization of (re)myelination in acute and organotypic brain slices(m/w/x)
Full-timeInternshipOn-siteBasel - 1201 F. Hoffmann-La Roche AG
PhD Internship for Mathematics, Statistics PhD students - RiSE(m/w/x)
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