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F.F. Hoffmann-La Roche AG

RiSE Internship - Targeting CNS Meninges(m/w/x)

Basel
Full-timeInternshipOn-site

Exploratory lab work investigating CNS meninges targeting in vivo. Valid LTK1/FELASA B animal licence required. Internship experience, neuroscience/vascular biology proficiency, and extensive imaging methodologies experience.

Requirements

  • Master's degree less than a year ago or enrolled in PhD/medical program
  • Seeking industry internship experience
  • Valid LTK1/FELASA B animal licence
  • Proficiency in neuroscience and/or vascular biology
  • Extensive imaging methodologies experience including whole mount immunofluorescence stainings
  • Good knowledge of imaging dataset analysis methods
  • Experience with dural/leptomeningeal biology and anatomy (beneficial)
  • Passion for answering fundamental neurovascular biology questions with high translational impact
  • Performing animal work (LTK1 or similar required)

Tasks

  • Perform exploratory lab work
  • Investigate targeting of CNS meninges in vivo
  • Visualize cranio-meningeal compartment
  • Explore suitable delivery methods
  • Conduct animal work (LTK1 or similar required)
  • Optimize dissection and staining conditions
  • Apply state-of-the-art imaging techniques
  • Use confocal microscopy
  • Utilize tissue clearing and lightsheet microscopy
  • Analyze intact cranio-meningeal compartment
  • Summarize work for internal and external meetings
  • Draft a publication
  • Collaborate with a Roche scientist mentor

Education

  • Currently in higher education

Languages

  • EnglishBusiness Fluent

Tools & Technologies

  • neuroscience
  • vascular biology
  • imaging methodologies
  • whole mount immunofluorescence stainings
  • dural/leptomeningeal biology
  • leptomeningeal anatomy
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