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BOBoehringer Ingelheim

Senior / Principal Scientist - Preclinical PK/PD Modelling and Simulation(m/w/x)

Biberach
Full-timeOn-siteSenior

Performing PK/PD modelling and simulation for drug candidate development. Human PK and dose predictions essential. Industry experience preferred, with strong biology and DMPK knowledge.

Requirements

  • PhD in preclinical PK/PD modelling
  • Several years of relevant PK/PD modelling experience
  • Industry experience beneficial
  • Solid knowledge in biology, DMPK, or pharmacology
  • Proven skills in PK, PK/PD, PBPK, or longitudinal disease modelling
  • Proficiency in programming languages and pharmacometric tools
  • Authentic, enthusiastic, cooperative, creative personality
  • Excellent communication skills in English
  • PhD in preclinical PK/PD modelling, pharmacometrics, applied mathematics, systems biology, bioinformatics or similar
  • Long-term experience in preclinical PK/PD modelling, pharmacometrics, applied mathematics, systems biology, bioinformatics or similar
  • Industry experience beneficial
  • In-depth understanding of preclinical PK/PD modelling and simulation
  • In-depth understanding of pharmacology and DMPK- or NBE PK- related topics
  • Experience in working in matrix-style project teams
  • Experience in leading matrix-style project teams
  • Applications from people with severe disabilities warmly welcomed
  • Preferential consideration for severely disabled applicants in case of equal qualifications

Tasks

  • Perform high-quality PK/PD modelling and simulation analyses
  • Support research projects with informative study designs
  • Conduct human PK and dose predictions
  • Contribute to understanding PK/PD relations of candidate drugs
  • Achieve modelling-related goals for Discovery Research
  • Represent Preclinical PK/PD Modelling in international teams
  • Coordinate Research DMPK or NBE PK in international teams
  • Establish and maintain external collaborations
  • Support licensing activities
  • Lead coordination of Drug Discovery Sciences disciplines
  • Shape and implement PK/PD modelling strategies
  • Define modelling-related goals for Discovery Research
  • Coach and support development of junior research scientists

Work Experience

  • approx. 4 - 6 years

Education

  • Doctoral / PhD

Languages

  • EnglishBusiness Fluent

Tools & Technologies

  • R
  • MATLAB
  • Phoenix WinNonLin
  • NONMEM
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