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Boehringer Ingelheim
13d ago

Postdoc - AAV vectors for drug discovery research(m/w/x)

Biberach
Full-timeOn-siteJunior

Description

You will drive therapeutic innovation by engineering AAV vectors and conducting in vivo studies, playing a vital role in validating drug targets within a dynamic pharma research environment.

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Requirements

  • •PhD in molecular biology, biotechnology, biochemistry or related discipline
  • •Knowledge of molecular and cell biological techniques and animal or tissue handling
  • •Experience with AAV vectors, viral vector systems, or capsid engineering
  • •Confidence in handling complex and large data sets
  • •Track record of publications in peer-reviewed journals
  • •Multidisciplinary teamwork and excellent communication skills
  • •Fluency in English and German skills

Education

Doctoral / PhD

Tasks

  • •Design strategies for pan-tissue transducing AAV vectors
  • •Utilize in silico design and directed evolution
  • •Produce and purify AAV preparations
  • •Analyze AAV preparations for quality
  • •Conduct in vivo studies in mice
  • •Select and characterize promising vector candidates
  • •Apply DNA, RNA, and protein-based readouts
  • •Perform qPCR and in situ hybridization
  • •Execute sequencing and immunohistochemistry
  • •Modulate genes using overexpression and CRISPR-knockouts
  • •Validate drug targets for early research
  • •Participate in the global postdoctoral program
  • •Present research at the company's Postdoc days

Tools & Technologies

AAV vectorsviral vector systemscapsid engineering

Languages

English – Business Fluent

German – Basic

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