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Principal Scientist, Mid/Large Scale Oligonucleotide Synthesis, xRNA Therapeutics(m/w/x)
Overseeing facility operations for mid/large scale siRNA product synthesis and purification, delivering for in vitro and in vivo evaluation. PhD in synthetic chemistry focused on oligonucleotides, with practical solid phase synthesis and downstream processing experience required. Budget management for capital and consumables, leading a team of scientists.
Requirements
- PhD in synthetic chemistry focused on oligonucleotides
- Practical experience in oligonucleotide solid phase synthesis and downstream processing
- Demonstrated leadership abilities
- Capacity to promote and implement innovative ideas
- Strong independent problem-solving skills
- Proven collaborative attitude
- Proficiency in managing multiple priorities effectively
- Excellent verbal and written communication abilities
Tasks
- Oversee the oligonucleotide synthesis facility
- Manage capital and consumables budgets
- Lead a team of scientists in oligonucleotide synthesis and purification
- Deliver high-quality siRNA products for in vitro screening
- Deliver siRNA products for in vivo evaluation
- Collaborate with xRNA and oligonucleotide synthesis teams in Basel and Cambridge
- Provide technical leadership to the scale-up team
- Optimize methodologies and processes for improved efficiencies
- Collaborate with synthetic chemists to scale up new siRNA chemistries
- Facilitate the transition of new chemistries into development
- Document and communicate results to stakeholders
- Prepare patent applications and scientific publications
- Mentor team members by sharing technical expertise
Work Experience
- 2 - 3 years
Education
- Doctoral / PhD
Languages
- English – Business Fluent
Not a perfect match?
- NovartisFull-timeOn-siteExperiencedBasel
- Novartis Pharma AG
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Principal Scientist, Mid/Large Scale Oligonucleotide Synthesis, xRNA Therapeutics(m/w/x)
Overseeing facility operations for mid/large scale siRNA product synthesis and purification, delivering for in vitro and in vivo evaluation. PhD in synthetic chemistry focused on oligonucleotides, with practical solid phase synthesis and downstream processing experience required. Budget management for capital and consumables, leading a team of scientists.
Requirements
- PhD in synthetic chemistry focused on oligonucleotides
- Practical experience in oligonucleotide solid phase synthesis and downstream processing
- Demonstrated leadership abilities
- Capacity to promote and implement innovative ideas
- Strong independent problem-solving skills
- Proven collaborative attitude
- Proficiency in managing multiple priorities effectively
- Excellent verbal and written communication abilities
Tasks
- Oversee the oligonucleotide synthesis facility
- Manage capital and consumables budgets
- Lead a team of scientists in oligonucleotide synthesis and purification
- Deliver high-quality siRNA products for in vitro screening
- Deliver siRNA products for in vivo evaluation
- Collaborate with xRNA and oligonucleotide synthesis teams in Basel and Cambridge
- Provide technical leadership to the scale-up team
- Optimize methodologies and processes for improved efficiencies
- Collaborate with synthetic chemists to scale up new siRNA chemistries
- Facilitate the transition of new chemistries into development
- Document and communicate results to stakeholders
- Prepare patent applications and scientific publications
- Mentor team members by sharing technical expertise
Work Experience
- 2 - 3 years
Education
- Doctoral / PhD
Languages
- English – Business Fluent
About the Company
Novartis Pharma AG
Industry
Pharmaceuticals
Description
Das Unternehmen setzt sich für Vielfalt, Chancengleichheit und Inklusion ein und fördert innovative Lösungen zur Verbesserung der Patientenversorgung.
Not a perfect match?
- Novartis
Principal Scientist - Mid/Large Scale Oligonucleotide Synthesis, xRNA Therapeutics(m/w/x)
Full-timeOn-siteExperiencedBasel - Novartis Pharma AG
Senior Scientist – Small Scale Oligonucleotide Synthesis(m/w/x)
Full-timeOn-siteSeniorBasel - Novartis Pharma AG
Senior Scientist - xRNA /sIRNA Discovery(m/w/x)
Full-timeOn-siteSeniorBasel - Novartis Pharma AG
Senior Scientist - xRNA /sIRNA Discovery(m/w/x)
Full-timeOn-siteSeniorBasel - Novartis
Principal Scientist - Oncology Translational Research(m/w/x)
Full-timeOn-siteExperiencedBasel