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NONovartis Pharma AG

Senior Scientist - xRNA /sIRNA Discovery(m/w/x)

Basel
Full-timeOn-siteSenior
AI/ML

Developing and validating cell-based assays for xRNA/siRNA discovery, including transfection and qPCR, at a biotech firm. Minimum 3-5 years lab research in pharma/biotech with mammalian cell culture and mRNA/protein isolation experience required. Inclusive work environment, focus on patient care.

Requirements

  • MS or Bachelor's/scientific apprenticeship with at least 5 years of industry experience or recent graduate PhD with 0-1 years of industry experience
  • Minimum of 3-5 years of laboratory research experience in pharma or biotech industry
  • Strong hands-on experience in cell and molecular biology techniques
  • Mammalian and primary cell culture
  • mRNA and protein isolation, characterization and quantification
  • Next-generation sequencing workflows
  • Experience with liquid-handling systems and automation of cell-based assays or strong interest in developing such
  • Proven ability to troubleshoot and refine assays
  • Strong competence in MS Office applications and data analysis software
  • Excellent organizational skills and attention to detail
  • Ability to collaborate and thrive in a fast-paced, team-oriented research environment
  • Familiarity with primary cell culture models
  • Exposure to bioinformatics and coding for data processing, visualization and analysis
  • Experience with specific automation platforms is a strong plus

Tasks

  • Design and execute siRNA screening experiments
  • Conduct cell-based transfection assays
  • Perform qPCR and reporter-based readouts
  • Develop and optimize biochemical assays
  • Validate cell-based assays for siRNA discovery
  • Contribute to automated workflows with liquid-handling robotics
  • Drive improvements in lab organization and workflows
  • Implement new technologies and equipment
  • Collaborate with an interdisciplinary team
  • Present data and conclusions clearly in verbal and written form
  • Maintain high-quality records in electronic lab notebooks
  • Analyze and report results in a timely manner

Work Experience

  • 3 - 5 years

Education

  • Bachelor's degree

Languages

  • EnglishBusiness Fluent

Tools & Technologies

  • qPCR
  • CLIP
  • IP
  • ELISA
  • Western blot
  • NGS library preparation
  • BioMek
  • Opentrons
  • GraphPad Prism
  • Spotfire
Find the original job posting in its most current version here. Nejo automatically captured this job from the website of Novartis Pharma AG and processed the information on Nejo with the help of AI for you. Despite careful analysis, some information may be incomplete or inaccurate. Please always verify all details in the original posting! Content and copyrights of the original posting belong to the advertising company.

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