Description

In this role, you will lead a dynamic team in a cutting-edge oligonucleotide synthesis facility, focusing on delivering high-quality siRNA products. Your day-to-day responsibilities will involve collaborating with multidisciplinary teams, optimizing processes, and mentoring scientists to advance innovative therapies.

Requirements

• •PhD in synthetic chemistry focused on oligonucleotides
• •Practical experience in oligonucleotide solid phase synthesis and downstream processing
• •Demonstrated leadership abilities
• •Capacity to promote and implement innovative ideas
• •Strong independent problem-solving skills
• •Proven collaborative attitude
• •Proficiency in managing multiple priorities effectively
• •Excellent verbal and written communication abilities

Tasks

• •Oversee the oligonucleotide synthesis facility
• •Manage capital and consumables budgets
• •Lead a team of scientists in oligonucleotide synthesis and purification
• •Deliver high-quality siRNA products for in vitro screening
• •Deliver siRNA products for in vivo evaluation
• •Collaborate with xRNA and oligonucleotide synthesis teams in Basel and Cambridge
• •Provide technical leadership to the scale-up team
• •Optimize methodologies and processes for improved efficiencies
• •Collaborate with synthetic chemists to scale up new siRNA chemistries
• •Facilitate the transition of new chemistries into development
• •Document and communicate results to stakeholders
• •Prepare patent applications and scientific publications
• •Mentor team members by sharing technical expertise