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121201 F. Hoffmann-La Roche AG

Postdoc position in Applied Organoid Technologies group(m/w/x)

Basel
Full-timeOn-siteExperienced

Modeling airway biology with organoids for COPD/infectious diseases, phenotyping complex tissues using clearing and single-cell technologies. Hands-on expertise in tissue bioengineering, hydrogels, and human lung models required. Access to advanced tissue clearing, imaging, and single-cell technologies.

Requirements

  • PhD in cellular biology, stem cell biology, tissue bioengineering, or relevant field
  • Hands-on expertise in tissue bioengineering, hydrogels, and human models of the lung
  • Experience in design and execution of projects modeling airway relevant biology in vitro
  • Methods for phenotyping complex tissues using tissue clearing, imaging, single cell technologies, flow cytometry, and microscopy
  • Strong critical thinking, communication, organization, and presentation skills

Tasks

  • Design and execute projects modeling airway-relevant biology
  • Utilize in vitro methods for studying COPD, infectious diseases, and inflammation
  • Phenotype complex tissues using tissue clearing techniques
  • Conduct whole-mount imaging and single-cell technologies
  • Perform flow cytometry and high-resolution microscopy
  • Expand expertise in human airway models and related biology
  • Leverage Roche R&D ecosystem for hypothesis generation and model evaluation
  • Convert organoid-based models into assays for drug development

Work Experience

  • approx. 1 - 4 years

Education

  • Doctoral / PhD

Languages

  • EnglishBusiness Fluent
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