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121201 F. Hoffmann-La Roche AG

Post Doctorate Scientist, On-chip Organoid Patterning(m/w/x)

Basel
Full-timeOn-siteExperienced

Microfluidic chip fabrication with photo/soft lithography and DRIE etching for human neural organoid cultures. PhD in Bioengineering and strong clean room experience required. Access to advanced clean room facilities.

Requirements

  • Motivation and collaboration skills
  • PhD in Bioengineering or related field
  • Expertise in neural organoid culture
  • Strong clean room experience
  • Background in microfluidic device development
  • Fluency in oral and written English

Tasks

  • Design and fabricate advanced microfluidic chips for organ-on-a-chip applications
  • Generate human neural organoid cultures and optimize complex culture protocols
  • Perform molecular phenotyping of on-chip generated model systems
  • Conduct 3D modeling and simulations using AutoCAD, Blender, or COMSOL
  • Lead microengineering tasks using clean room techniques such as photo/soft lithography and DRIE etching
  • Utilize advanced imaging techniques, including confocal and light sheet microscopy
  • Execute tissue sectioning and fluorescence in situ hybridization experiments
  • Collaborate across the institute to integrate single-cell genomics data into chip development

Work Experience

  • approx. 1 - 4 years

Education

  • Doctoral / PhD

Languages

  • EnglishBusiness Fluent
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