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ISIsomorphic Labs

PKPD Modelling Lead(m/w/x)

Lausanne
Full-timeWith Home OfficeManagement
AI/ML

Designing quantitative pharmacology strategies for biologics projects, leveraging frontier AI in drug discovery. 3+ years of pharmaceutical industry experience with advanced PK/PD knowledge required. Focus on frontier AI applications in drug discovery.

Requirements

  • PhD in Pharmaceutical Science or related field
  • 3+ years of pharmaceutical industry experience
  • Experience as a PKPD Lead in biologics
  • Practical experience in quantitative pharmacology
  • Advanced knowledge of PK and PKPD modelling
  • Good understanding of machine learning techniques
  • Familiarity with Python and KNIME

Tasks

  • Design and implement quantitative pharmacology strategies.
  • Provide scientific leadership for biologics projects.
  • Collaborate with teams to resolve PK and PD challenges.
  • Develop advanced PKPD models for various projects.
  • Contribute to modality selection for each target.
  • Integrate PK, PD, and toxicological data for decision-making.
  • Author PKPD sections of regulatory documents.
  • Partner with Machine Learning to enhance predictive models.
  • Identify integration methods for platform improvements.
  • Support biologics developability platform development.
  • Ensure timely data generation for portfolio projects.
  • Leverage external collaborators' expertise for team impact.
  • Oversee data generation campaigns for AI models.
  • Mentor junior DMPK and Quantitative Pharmacology members.
  • Champion a culture of inclusion and professional development.

Work Experience

  • 3 years

Education

  • Doctoral / PhD

Languages

  • EnglishBusiness Fluent

Tools & Technologies

  • Python
  • KNIME
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