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DMPK Lead(m/w/x)
Implementing AI-first strategies for drug discovery at biotech firm applying frontier AI, analyzing PD/toxicological data. PhD in Pharmaceutical Science or Chemistry, plus developing DMPK/quantitative pharmacology packages required. Work with frontier AI for deeper scientific insights.
Requirements
- PhD in Pharmaceutical Science, Pharmacy, Chemistry, or relevant subject
- 3+ years' professional experience as DMPK Lead
- Experience developing DMPK and quantitative pharmacology packages
- Experience partnering with Preclinical and Clinical teams
- In depth knowledge of biotransformation
- In depth knowledge of PK modelling
- Experience with biologics, peptides and new modalities
- Advanced knowledge of PKPD modelling
- Good understanding of machine learning techniques
- Familiarity with Python and KNIME
Tasks
- Design and implement AI-first DMPK strategies
- Integrate quantitative pharmacology into project strategies
- Design screening cascades and mechanistic experiments
- Analyze DMPK, PD, and toxicological data
- Predict clinical doses and safety windows
- Define Quantitative Pharmacology strategies with Pharmacology Leads
- Leverage company datasets to solve DMPK questions
- Optimize molecule design with Chemistry Leads
- Maintain expertise in human PK prediction methods
- Author DMPK sections for regulatory documents
- Promote inclusion and continuous professional development
Work Experience
- 3 years
Education
- Doctoral / PhD
Languages
- English – Business Fluent
Tools & Technologies
- Python
- KNIME
- Machine learning techniques
Benefits
Other Benefits
- Disability accommodation
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DMPK Lead(m/w/x)
Implementing AI-first strategies for drug discovery at biotech firm applying frontier AI, analyzing PD/toxicological data. PhD in Pharmaceutical Science or Chemistry, plus developing DMPK/quantitative pharmacology packages required. Work with frontier AI for deeper scientific insights.
Requirements
- PhD in Pharmaceutical Science, Pharmacy, Chemistry, or relevant subject
- 3+ years' professional experience as DMPK Lead
- Experience developing DMPK and quantitative pharmacology packages
- Experience partnering with Preclinical and Clinical teams
- In depth knowledge of biotransformation
- In depth knowledge of PK modelling
- Experience with biologics, peptides and new modalities
- Advanced knowledge of PKPD modelling
- Good understanding of machine learning techniques
- Familiarity with Python and KNIME
Tasks
- Design and implement AI-first DMPK strategies
- Integrate quantitative pharmacology into project strategies
- Design screening cascades and mechanistic experiments
- Analyze DMPK, PD, and toxicological data
- Predict clinical doses and safety windows
- Define Quantitative Pharmacology strategies with Pharmacology Leads
- Leverage company datasets to solve DMPK questions
- Optimize molecule design with Chemistry Leads
- Maintain expertise in human PK prediction methods
- Author DMPK sections for regulatory documents
- Promote inclusion and continuous professional development
Work Experience
- 3 years
Education
- Doctoral / PhD
Languages
- English – Business Fluent
Tools & Technologies
- Python
- KNIME
- Machine learning techniques
Benefits
Other Benefits
- Disability accommodation
About the Company
Isomorphic Labs
Industry
Pharmaceuticals
Description
The company is applying frontier AI to unlock deeper scientific insights and accelerate drug discovery.
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