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Isomorphic Labs
yesterday

Computational Drug Designer(m/w/x)

Lausanne
Full-timeWith Home OfficeSenior
AI/ML
Data Science

Description

By applying cutting-edge AI to real-world drug discovery, you will provide the strategic direction and scientific expertise needed to design novel molecules and solve complex biological challenges.

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Requirements

  • PhD in Computational, Medicinal, Synthetic Organic Chemistry, or equivalent industrial experience
  • 5+ years industrial experience in computational chemistry (CADD)
  • Strong foundational knowledge of modern computational chemistry
  • Proven track record in structure-based drug design (SBDD)
  • Experience writing Python scripts or utilizing pipelining tools
  • Passion for applying AI/ML to drug design
  • Excellent communication and interpersonal skills
  • Strong growth mindset and eagerness to learn
  • Experience managing activities at CROs (Nice to have)
  • Familiarity with medicinal chemistry techniques (Nice to have)
  • Knowledge of specific drug discovery approaches (Nice to have)
  • Basic understanding of DMPK principles (Nice to have)
  • Fluency in Python for tool development (Nice to have)
  • Track record of scientific authorship or inventorship (Nice to have)

Education

Doctoral / PhD

Tasks

  • Apply modern drug design principles to advance programs
  • Utilize state-of-the-art AI for computational drug design
  • Provide strategic direction to the platform teams
  • Collaborate with internal and third-party organizations
  • Deliver data-driven designs and technical solutions
  • Prepare detailed scientific proposals and reports
  • Mentor and support the development of junior colleagues
  • Champion a culture of inclusion and professional development

Tools & Technologies

Pythoncheminformaticsvirtual screeningdockingmachine learning modelsstructure-based drug design (SBDD)pipelining toolsAI/MLdata analysis softwareADMET principlesfragment-based drug design (FBDD)PROTACsmolecular gluesPPI inhibitorsDMPK principles

Languages

EnglishBusiness Fluent

Benefits

Flexible Working

  • Hybrid working model
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