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NONovartis Pharma AG

Therapeutic Area Biomarker Lead / Biomarker Strategy – Cardiovascular and Metabolism(m/w/x)

Basel
Vollzeitmit HomeofficeManagement
Data Science

Leading CVM disease area biomarker matrix team and developing biomarker strategies. MD, MD/PhD, or PhD degree with 5+ years leadership experience required. Interface for project transition and core member of clinical project teams.

Anforderungen

  • MD, MD/PhD, or PhD degree
  • Deep understanding of cardiovascular and metabolic disease epidemiology
  • Scientific excellence with high quality publications
  • Clinical and/or biological expertise in cardiovascular and metabolic diseases
  • 5+ years independent leadership experience
  • External leadership/partnership in consortia and/or health authority initiatives
  • Leading and partnering in multidisciplinary matrix teams
  • Own entire section of portfolio and phase package
  • Well-developed interpersonal skills
  • Good presence and ability to influence and negotiate
  • Experienced presenter and communicator
  • Significant relevant experience after MD/PhD/postdoc
  • Quantitative expertise in biostatistics, bioinformatics, computer biology, statistical genetics, clinical imaging, machine learning, or data science
  • Interpreting and publishing studies with 'omics' data
  • Closely partnering with/leading data scientists
  • Fluent oral and written English

Aufgaben

  • Lead the CVM disease area biomarker matrix team
  • Develop and implement biomarker strategies
  • Provide interface for project transition
  • Serve as a core member of CVM clinical project teams
  • Engage in Translational Data Science teams
  • Provide therapeutic area line function review for clinical protocols
  • Identify, develop, and drive disease biology
  • Identify, develop, and drive mechanistic biology
  • Identify, develop, and drive compound biology
  • Support clinical approaches for the CVM portfolio
  • Support precision medicine approaches for the CVM portfolio
  • Deliver clinical project biomarker strategies
  • Deliver disease biomarker strategies
  • Deliver biomarker plans across early through late phase
  • Support relevant mature assets in the late phase portfolio
  • Lead a matrixed group of Subject Matter Experts
  • Lead project team representatives
  • Lead key program stakeholders
  • Develop biomarkers strategies for disease
  • Develop biomarkers strategies for assets
  • Represent Biomarker Development on Disease Area Decision Boards
  • Drive cardiovascular and metabolic disease biology
  • Drive compound mechanistic biology
  • Drive precision medicine approaches for the portfolio
  • Lead strategic translational data working groups
  • Integrate large-scale patient multi-modal data sets
  • Analyze large-scale patient multi-modal data sets
  • Identify new indications from data analysis
  • Identify new endpoints from data analysis
  • Identify responsive patient subpopulations from data analysis
  • Represent BMD line functions in Therapeutic Area Line Function committees
  • Lead biomarker strategies at the clinical team level
  • Drive biomarker plans at the clinical team level
  • Contribute to BMD/TM/BR wide initiatives
  • Stay up to date on scientific literature
  • Stay up to date on competitor data
  • Implement strategies with the BMD global organization
  • Design the RDC biomarker strategy for transitioning assets
  • Design the RDC biomarker strategy for mature assets
  • Ensure study level alignment across the portfolio segment

Berufserfahrung

  • 5 Jahre

Ausbildung

  • Bachelor-Abschluss

Sprachen

  • Englischfließend

Tools & Technologien

  • biostatistics
  • bioinformatics
  • computer biology
  • statistical genetics
  • clinical imaging
  • machine learning
  • data science
  • omics data
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