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BOBoehringer Ingelheim

Senior Scientist/Principal Scientist(m/w/x)

Biberach
Full-timeOn-siteSenior

Advancing mass spectrometry methods and LC-MS sample preparation for first-in-class drug discovery. PhD in proteomics and multiyear leadership experience required. Supervision of technical staff in cross-functional teams.

Requirements

  • PhD in mass spectrometry-based proteomics, biochemistry or pharmacology
  • Multiyear drug discovery and leadership experience
  • Experience with state-of-the-art proteomics workflows
  • Experience in sample preparation for LC-MS
  • Analytical mindset and interdisciplinary collaboration skills
  • Conceptual understanding of biomarkers (asset)
  • Understanding of biochemistry and molecular mechanisms
  • Critical thinking and motivation to innovate
  • Excellent data analysis and presentation skills
  • Fluent English and German (a plus)
  • Motivation and passion for biomarker research

Tasks

  • Represent your scientific discipline in cross-functional teams
  • Advance cutting-edge methods in proteomics and mass spectrometry
  • Shape first-in-class opportunities across the discovery portfolio
  • Lead and supervise technical and scientific staff
  • Provide scientific leadership to peers
  • Review requests for biomarker discovery and quantitation
  • Align project goals with internal partners
  • Design and execute proteomics experiments
  • Analyze biomarker discovery and targeted quantification data
  • Identify PTMs and determine interactomes
  • Operate cutting-edge Orbitrap and QTOF mass spectrometry platforms
  • Utilize expert analysis software for mass spectrometry
  • Use Omics-platforms for translational topics and NTC confirmation
  • Perform functional validation and MoA elucidation
  • Advance scientific and proteomics workflows through innovation
  • Educate and train colleagues in proteomic analysis
  • Develop ongoing scientific and drug development expertise
  • Lead technicians, students, interns, and Postdocs
  • Guide scientific development and implementation of concepts
  • Drive innovations and cross-functional strategies independently

Work Experience

approx. 4 - 6 years

Education

Master's degree

Languages

EnglishBusiness FluentGermanBasic

Tools & Technologies

mass spectrometrydata-independent acquisition (DIA)Thermo orbitrap Astral mass spectrometerLC-MS
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