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PRProteros biostructures GmbH

Research Scientist Biochemistry with Focus Plate-Based Assays(m/w/x)

München
Full-timeOn-siteJunior

Developing biochemical binding and functional assays for early drug discovery projects. PhD in biochemistry or comparable discipline required. Multicultural teams, open corporate culture.

Requirements

  • PhD degree in biochemistry, biophysics or comparable discipline
  • Familiarity with drug discovery process (screen to lead)
  • Advanced experience with biochemical and biophysical technologies
  • Deep understanding of enzymology and binding kinetics
  • Experience integrating biochemical/biophysical technologies into early drug discovery
  • Ability to plan experiments and generate biochemical/biophysical data
  • Ability to analyze biochemical/biophysical data
  • Ability to report biochemical/biophysical data to drug discovery teams
  • Experience discussing data from neighboring disciplines
  • Experience integrating own data into drug discovery projects
  • Positive, communicative, and open personality
  • Ability to understand other opinions
  • Contribution to productive project discussions

Tasks

  • Develop biochemical binding and functional assays
  • Create biophysical assay formats
  • Support internal and customer early drug discovery projects
  • Focus on plate-based assays for profiling and library screening
  • Assess target-ligand binding and ligand effects on enzymatic activity
  • Utilize techniques like TR-FRET, AlphaLisa, luminescence, FI, FP, FRET/BRET
  • Apply biophysical techniques (nanoDSF, TSA, MST, ITC, SPR) as needed
  • Work in a state-of-the-art biochemistry and biophysics platform
  • Perform experiments and instruct lab staff
  • Analyze and report results to customers and internal teams

Work Experience

  • 1 - 2 years

Education

  • Doctoral / PhD

Languages

  • EnglishNative
  • GermanBasic

Benefits

Other Benefits

  • Comprehensive onboarding

Informal Culture

  • Multicultural teams
  • Open corporate culture
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