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PhD Position – Shaping the Colorectal Niche(m/w/x)
Cultivating patient-derived colon and tumor organoids, isolating extracellular vesicles via ultracentrifugation at a university hospital research lab. Advanced 3D cell culture and microbiology experience required. Access to high-resolution confocal immunofluorescence.
Requirements
- Master's degree in related scientific discipline
- Experience in advanced 3D cell culture
- Ideally handling patient-derived organoids
- Experience in microbiology or bacterial culture
- Ideally biochemical techniques for vesicle isolation
- Background in computational biology or bioinformatics
- Interest in analyzing large NGS datasets
- Proficiency in molecular biology standard methods
- Proficiency in imaging techniques
- Excellent English communication skills
- Team spirit and structured working style
Tasks
- Cultivate patient-derived colon and tumor organoids
- Generate specialized apical-out and apical-in organoid models
- Isolate extracellular vesicles using ultracentrifugation techniques
- Work with wild and bioengineered bacterial strains
- Quantify genotoxic effects using high-resolution confocal immunofluorescence
- Characterize nanoparticles via TEM, NTA, and functional assays
- Perform bulk RNA and single-cell whole-genome sequencing
- Analyze proteomics and metabolomics data using bioinformatics pipelines
Education
- Master's degree
Languages
- English – Business Fluent
Tools & Technologies
- 3D cell culture
- patient-derived organoids
- ultracentrifugation
- Next-Generation Sequencing
- RNA-seq
- single-cell WGS
- metagenomics
- machine learning algorithms
- qPCR
- confocal microscopy
- IHC
Not a perfect match?
- Universitätsklinikum ErlangenPart-timeOn-siteNot specifiedErlangen
- Universitätsklinikum Erlangen
Doktorand(m/w/x)
Part-timeTemporary contractOn-siteNot specifiedErlangen - FAU Erlangen-Nuremberg/CITABLE
PhD Student for super-resolution microscopy-based investigations of the glycocalyx(m/w/x)
Part-timeOn-siteNot specifiedErlangen - Universitätsklinikum Erlangen
Naturwissenschaftlicher Doktorand / PhD position “long-lived RNAs in motor neuron diseases”(m/w/x)
Part-timeOn-siteNot specifiedErlangen - Uniklinikum Erlangen
Bioinformatics Scientist - PhD candidate(m/w/x)
Part-timeOn-siteNot specifiedErlangen
PhD Position – Shaping the Colorectal Niche(m/w/x)
Cultivating patient-derived colon and tumor organoids, isolating extracellular vesicles via ultracentrifugation at a university hospital research lab. Advanced 3D cell culture and microbiology experience required. Access to high-resolution confocal immunofluorescence.
Requirements
- Master's degree in related scientific discipline
- Experience in advanced 3D cell culture
- Ideally handling patient-derived organoids
- Experience in microbiology or bacterial culture
- Ideally biochemical techniques for vesicle isolation
- Background in computational biology or bioinformatics
- Interest in analyzing large NGS datasets
- Proficiency in molecular biology standard methods
- Proficiency in imaging techniques
- Excellent English communication skills
- Team spirit and structured working style
Tasks
- Cultivate patient-derived colon and tumor organoids
- Generate specialized apical-out and apical-in organoid models
- Isolate extracellular vesicles using ultracentrifugation techniques
- Work with wild and bioengineered bacterial strains
- Quantify genotoxic effects using high-resolution confocal immunofluorescence
- Characterize nanoparticles via TEM, NTA, and functional assays
- Perform bulk RNA and single-cell whole-genome sequencing
- Analyze proteomics and metabolomics data using bioinformatics pipelines
Education
- Master's degree
Languages
- English – Business Fluent
Tools & Technologies
- 3D cell culture
- patient-derived organoids
- ultracentrifugation
- Next-Generation Sequencing
- RNA-seq
- single-cell WGS
- metagenomics
- machine learning algorithms
- qPCR
- confocal microscopy
- IHC
About the Company
Universitätsklinikum Erlangen
Industry
Healthcare
Description
Das Unternehmen bietet Patientenversorgung auf höchstem Niveau, ausgezeichnete Forschung und Lehre sowie modernste Medizin und Diagnostik.
Not a perfect match?
- Universitätsklinikum Erlangen
PhD Position in Medical Molecular Biology / Immuno-Oncology(m/w/x)
Part-timeOn-siteNot specifiedErlangen - Universitätsklinikum Erlangen
Doktorand(m/w/x)
Part-timeTemporary contractOn-siteNot specifiedErlangen - FAU Erlangen-Nuremberg/CITABLE
PhD Student for super-resolution microscopy-based investigations of the glycocalyx(m/w/x)
Part-timeOn-siteNot specifiedErlangen - Universitätsklinikum Erlangen
Naturwissenschaftlicher Doktorand / PhD position “long-lived RNAs in motor neuron diseases”(m/w/x)
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