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PhD Position – Shaping the Colorectal Niche(m/w/x)
Cultivating patient-derived colon and tumor organoids, isolating extracellular vesicles via ultracentrifugation at a university hospital research lab. Advanced 3D cell culture and microbiology experience required. Access to high-resolution confocal immunofluorescence.
Requirements
- Master's degree in related scientific discipline
- Experience in advanced 3D cell culture
- Ideally handling patient-derived organoids
- Experience in microbiology or bacterial culture
- Ideally biochemical techniques for vesicle isolation
- Background in computational biology or bioinformatics
- Interest in analyzing large NGS datasets
- Proficiency in molecular biology standard methods
- Proficiency in imaging techniques
- Excellent English communication skills
- Team spirit and structured working style
Tasks
- Cultivate patient-derived colon and tumor organoids
- Generate specialized apical-out and apical-in organoid models
- Isolate extracellular vesicles using ultracentrifugation techniques
- Work with wild and bioengineered bacterial strains
- Quantify genotoxic effects using high-resolution confocal immunofluorescence
- Characterize nanoparticles via TEM, NTA, and functional assays
- Perform bulk RNA and single-cell whole-genome sequencing
- Analyze proteomics and metabolomics data using bioinformatics pipelines
Education
- Master's degree
Languages
- English – Business Fluent
Tools & Technologies
- 3D cell culture
- patient-derived organoids
- ultracentrifugation
- Next-Generation Sequencing
- RNA-seq
- single-cell WGS
- metagenomics
- machine learning algorithms
- qPCR
- confocal microscopy
- IHC
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PhD Position – Shaping the Colorectal Niche(m/w/x)
Cultivating patient-derived colon and tumor organoids, isolating extracellular vesicles via ultracentrifugation at a university hospital research lab. Advanced 3D cell culture and microbiology experience required. Access to high-resolution confocal immunofluorescence.
Requirements
- Master's degree in related scientific discipline
- Experience in advanced 3D cell culture
- Ideally handling patient-derived organoids
- Experience in microbiology or bacterial culture
- Ideally biochemical techniques for vesicle isolation
- Background in computational biology or bioinformatics
- Interest in analyzing large NGS datasets
- Proficiency in molecular biology standard methods
- Proficiency in imaging techniques
- Excellent English communication skills
- Team spirit and structured working style
Tasks
- Cultivate patient-derived colon and tumor organoids
- Generate specialized apical-out and apical-in organoid models
- Isolate extracellular vesicles using ultracentrifugation techniques
- Work with wild and bioengineered bacterial strains
- Quantify genotoxic effects using high-resolution confocal immunofluorescence
- Characterize nanoparticles via TEM, NTA, and functional assays
- Perform bulk RNA and single-cell whole-genome sequencing
- Analyze proteomics and metabolomics data using bioinformatics pipelines
Education
- Master's degree
Languages
- English – Business Fluent
Tools & Technologies
- 3D cell culture
- patient-derived organoids
- ultracentrifugation
- Next-Generation Sequencing
- RNA-seq
- single-cell WGS
- metagenomics
- machine learning algorithms
- qPCR
- confocal microscopy
- IHC
Like this job?
BetaYour Career Agent finds similar jobs for you every day.
About the Company
Universitätsklinikum Erlangen
Industry
Healthcare
Description
Das Unternehmen bietet Patientenversorgung auf höchstem Niveau, ausgezeichnete Forschung und Lehre sowie modernste Medizin und Diagnostik.
Not a perfect match?
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