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ADAdaptyv

.Scientist, Antibody Developability(m/w/x)

Lausanne
Full-timeOn-siteExperienced

Building antibody developability assessment panels using DSF, nanoDSF, SEC, HIC, AC-SINS, and DLS. Deep, hands-on antibody developability experience required. Automated lab operations, interdisciplinary collaboration.

Requirements

  • Deep, hands-on antibody developability experience
  • Applied industry experience in antibody discovery/engineering/development
  • Strong grasp of biologic developability
  • Ability to build and productize new capabilities
  • Interdisciplinary collaboration skills
  • Excitement about closing loop between wet-lab data and predictive models
  • Data fluency (scripting, structured datasets)

Tasks

  • Own antibody developability at Adaptyv
  • Build and validate developability assessment panel
  • Conduct thermostability tests using DSF and nanoDSF
  • Assess aggregation and self-association with SEC, HIC, AC-SINS, DLS
  • Evaluate polyreactivity and nonspecificity
  • Test solubility and chemical liability
  • Productize high-throughput developability service
  • Partner with lab automation for assay scaling and automation
  • Collaborate with software and ML teams to structure data
  • Connect developability data to computational predictions
  • Interpret results and advise customers on liabilities and risks
  • Guide customers on engineering next steps
  • Set scientific standards for trusted developability data

Work Experience

  • approx. 1 - 4 years

Education

  • Bachelor's degreeOR
  • Master's degree

Languages

  • EnglishBusiness Fluent
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