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121201 F. Hoffmann-La Roche AG

Scientist - Advanced in vitro Systems for Respiratory Research(m/w/x)

Basel
Full-timeOn-siteEntry Level

Developing advanced lung models and organoids from patient cells to induce disease phenotypes at a global pharma company. Extensive hands-on experience with complex in vitro systems and epithelial biology required. Access to proprietary research platforms.

Requirements

  • PhD degree in Life Sciences or closely related discipline
  • 0-4 years post-PhD experience
  • Strong technical and theoretical background in epithelial biology
  • Extensive hands-on experience with complex in vitro systems
  • Experience in lung epithelial barriers or mucosal immunology
  • Scientific accomplishments documented by publications in high-impact journals
  • Ability to present scientific data and concepts effectively
  • Fluency in English
  • Excellent data management and record-keeping skills
  • Ability to interact effectively with people
  • Experience with lab automation

Tasks

  • Develop advanced in vitro lung models
  • Validate and apply air-liquid interface cultures
  • Create organoids in co-culture with primary immune cells
  • Further develop in vitro models from patient cells
  • Maintain and induce disease phenotypes in models
  • Automate model generation processes
  • Establish quantitative in vitro assays for epithelial functions
  • Evaluate immune cell functions, including mucociliary clearance
  • Oversee genomic and drug screening in lung models
  • Analyze data using statistical methods
  • Present data in a format suitable for publication
  • Collaborate with Research Associates and Scientists

Education

  • Doctoral / PhD

Languages

  • EnglishBusiness Fluent
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