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121201 F. Hoffmann-La Roche AG

PhD Student - Immuno-Stem cell Dynamics Lab(m/w/x)

Basel
Full-timeOn-siteJunior

Applying novel live cell imaging and cellular bioengineering for organoid and primary cell cultures. MSc in life sciences, hands-on advanced in vitro systems experience, and familiarity with innate immune signaling pathways required. Collaboration with cross-functional teams at Roche.

Requirements

  • MSc in Biology, Biomedicine, Biochemistry, Bioinformatics, Biophysics, Chemistry, Physics, or related field
  • Strong academic performance (GPA >80%, first/upper second class degree, or top 10%)
  • At least 1 year of practical lab experience
  • Hands-on experience with advanced in vitro systems
  • Familiarity with innate immune signaling pathways and cancer biology
  • Experience with modern technologies (CRISPR/Cas9, single-cell or spatial transcriptomics, high-content imaging)
  • Experience with confocal or live-cell imaging and/or high-dimensional flow cytometry
  • Excellent English
  • Strong interpersonal and teamwork skills in international environments

Tasks

  • Apply novel live cell imaging techniques
  • Engage in cellular bioengineering
  • Perform organoid and primary cell cultures
  • Collaborate with cross-functional teams at Roche
  • Tackle challenges in antigen-antibody structure prediction
  • Design macromolecules generatively
  • Optimize antibodies
  • Analyze biological data from diverse sources
  • Provide insights to experimental biologists and bioinformaticians

Work Experience

  • 1 year

Education

  • Master's degree

Languages

  • EnglishBusiness Fluent

Tools & Technologies

  • CRISPR/Cas9
  • single-cell transcriptomics
  • spatial transcriptomics
  • high-content imaging
  • confocal imaging
  • live-cell imaging
  • high-dimensional flow cytometry
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