Novartis Pharma AG
Translational Medicine Academy fellow for Pharmacokinetics Sciences Modeling & Simulaton(m/w/x)
Full-timeOn-siteNot specified
Basel
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RORoche
Modelling and Simulations Scientist(m/w/x)
Basel
Full-timeOn-siteSenior
AI/ML
Data Science
Nejo AI Summary
Developing multi-scale PK, efficacy, and toxicology models for drug discovery. PhD-level degree in STEM and extensive mechanistic modeling experience required. Integration of experimental data from in vitro, in vivo, and omics studies.
Requirements
- PhD-level degree in natural sciences, mathematics, physical sciences, or engineering
- Advanced programming skills in R and Python, coding quickly and with high rigor
- Extensive experience in mechanistic modeling
- Strong mathematical foundation applied to drug discovery
- Ability to put complex results into drug development perspective
- Independent thinker with high creativity
- Track record of scientific excellence
- Strong lead author publication history
- Effective scientific communication skills
- Inclusive mindset
- Effective interaction with pharmacology scientists, project leaders, and collaborators
- Growth mindset with curiosity
- Willingness to learn and go beyond standard solutions
- Willingness to speak up and bring different perspectives
- Ability to lead consultants or outside collaborators effectively
- Proactive attitude with initiative
- Proposes solutions and maintains a "can-do" approach
- Independent thinker with scientific excellence track record
- Strong lead author publication history
Tasks
- Develop multi-scale models for PK, efficacy, and toxicology
- Integrate experimental data from in vitro, in vivo, and omics studies
- Build complex quantitative systems pharmacology (QSP) models
- Predict drug disposition and target attainment using mechanistic tumor-site interaction models
- Characterize drug accumulation and PK/PD relationships
- Extend modeling frameworks to combination therapies and antibody drug conjugates
- Design and deploy interactive tools using R and Shiny applications
- Leverage AI and Machine Learning for enhanced predictive accuracy
- Automate data integration and explore high-dimensional biological datasets
- Perform rigorous parameter estimation using Bayesian methods
- Communicate results to project teams and senior management
- Ensure M&S activities align with project goals and Roche standards
Work Experience
- approx. 4 - 6 years
Education
- Doctoral / PhD
Languages
- English – Business Fluent
Tools & Technologies
- R
- Python
Find the original job posting in its most current version here. Nejo automatically captured this job from the website of Roche and processed the information on Nejo with the help of AI for you. Despite careful analysis, some information may be incomplete or inaccurate. Please always verify all details in the original posting! Content and copyrights of the original posting belong to the advertising company.
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Not a perfect match?
- Novartis Pharma AG
Translational Medicine Academy fellow for Pharmacokinetics Sciences Modeling & Simulaton(m/w/x)
Full-timeOn-siteNot specifiedBasel - Roche
DMPK-PD Project Leader(m/w/x)
Full-timeOn-siteSeniorBasel - Novartis Pharma AG
Senior Expert - Science & Technology Upstream Process Modeling & Simulation(m/w/x)
Full-timeOn-siteSeniorBasel - 1201 F. Hoffmann-La Roche AG
Senior / Principal Cheminformatics Scientist(m/w/x)
Full-timeOn-siteSeniorBasel
RORoche
Modelling and Simulations Scientist(m/w/x)
Basel
Full-timeOn-siteSenior
AI/ML
Data Science
Nejo AI Summary
Developing multi-scale PK, efficacy, and toxicology models for drug discovery. PhD-level degree in STEM and extensive mechanistic modeling experience required. Integration of experimental data from in vitro, in vivo, and omics studies.
Requirements
- PhD-level degree in natural sciences, mathematics, physical sciences, or engineering
- Advanced programming skills in R and Python, coding quickly and with high rigor
- Extensive experience in mechanistic modeling
- Strong mathematical foundation applied to drug discovery
- Ability to put complex results into drug development perspective
- Independent thinker with high creativity
- Track record of scientific excellence
- Strong lead author publication history
- Effective scientific communication skills
- Inclusive mindset
- Effective interaction with pharmacology scientists, project leaders, and collaborators
- Growth mindset with curiosity
- Willingness to learn and go beyond standard solutions
- Willingness to speak up and bring different perspectives
- Ability to lead consultants or outside collaborators effectively
- Proactive attitude with initiative
- Proposes solutions and maintains a "can-do" approach
- Independent thinker with scientific excellence track record
- Strong lead author publication history
Tasks
- Develop multi-scale models for PK, efficacy, and toxicology
- Integrate experimental data from in vitro, in vivo, and omics studies
- Build complex quantitative systems pharmacology (QSP) models
- Predict drug disposition and target attainment using mechanistic tumor-site interaction models
- Characterize drug accumulation and PK/PD relationships
- Extend modeling frameworks to combination therapies and antibody drug conjugates
- Design and deploy interactive tools using R and Shiny applications
- Leverage AI and Machine Learning for enhanced predictive accuracy
- Automate data integration and explore high-dimensional biological datasets
- Perform rigorous parameter estimation using Bayesian methods
- Communicate results to project teams and senior management
- Ensure M&S activities align with project goals and Roche standards
Work Experience
- approx. 4 - 6 years
Education
- Doctoral / PhD
Languages
- English – Business Fluent
Tools & Technologies
- R
- Python
Find the original job posting in its most current version here. Nejo automatically captured this job from the website of Roche and processed the information on Nejo with the help of AI for you. Despite careful analysis, some information may be incomplete or inaccurate. Please always verify all details in the original posting! Content and copyrights of the original posting belong to the advertising company.
Like this job?
BetaYour Career Agent finds similar jobs for you every day.
About the Company
Roche
Industry
Pharmaceuticals
Description
The company is dedicated to advancing science and ensuring access to healthcare for everyone.
Not a perfect match?
- Novartis Pharma AG
Translational Medicine Academy fellow for Pharmacokinetics Sciences Modeling & Simulaton(m/w/x)
Full-timeOn-siteNot specifiedBasel - Novartis Pharma AG
Translational Medicine Academy fellow for Pharmacokinetics Sciences Modeling & Simulaton(m/w/x)
Full-timeOn-siteNot specifiedBasel - Roche
DMPK-PD Project Leader(m/w/x)
Full-timeOn-siteSeniorBasel - Novartis Pharma AG
Senior Expert - Science & Technology Upstream Process Modeling & Simulation(m/w/x)
Full-timeOn-siteSeniorBasel - 1201 F. Hoffmann-La Roche AG
Senior / Principal Cheminformatics Scientist(m/w/x)
Full-timeOn-siteSeniorBasel