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RORoche

Internship in Oligonucleotide Synthesis(m/w/x)

Basel
Full-timeInternshipOn-site

Discovering new techniques for oligonucleotide synthesis and scaling up processes for multi-gram quantities. BSc or MSc student or recent graduate with scientific interest required. Analytical method development using LC-MS, purification via chromatography.

Requirements

  • Enthusiasm and motivation
  • Scientific interest
  • Teamwork enjoyment
  • Strong willingness to learn
  • BSc or MSc student, or recent graduate
  • Chemistry or Biochemistry degree
  • Hands-on laboratory experience required
  • Oligonucleotide chemistry experience desirable
  • LC-MS analytics experience desirable
  • Excellent organizational skills
  • Proactive knowledge sharing
  • Excellent written communication skills in English
  • Excellent verbal communication skills in English
  • Mandatory internship certificate for non-EU/EFTA citizens
  • Continuous university enrollment for non-EU/EFTA citizens
  • Not suitable for thesis
  • Not suitable for PhD students
  • Not suitable for post-graduates

Tasks

  • Discover new techniques for oligonucleotide synthesis
  • Purify and analyze oligonucleotide reactions using advanced chromatography
  • Scale up synthesis processes for multi-gram quantities
  • Analyze complex synthetic oligonucleotides by LC-MS
  • Develop and implement innovative analytical methods
  • Conduct in-solution stability and hold-time studies

Education

  • Currently in higher educationOR
  • Bachelor's degree

Languages

  • EnglishBusiness Fluent

Tools & Technologies

  • Oligonucleotide chemistry
  • Solid phase synthesis
  • Conjugation
  • Purification
  • Analysis
  • LC-MS analytics
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