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RORoche

Chemistry Student Internship: Library Synthesis & Workflow Development(m/w/x)

Basel
Full-timeInternshipOn-site

Developing novel solid-supported reaction protocols and automated synthesis workflows for chemical libraries, bridging Medicinal Chemistry and Lead Discovery. Master's enrollment or graduation in Chemistry required, solid-phase synthesis experience a plus. Hands-on experience with automated workflows and multi-step organic syntheses.

Requirements

  • Master's enrollment or graduation in Chemistry
  • Ability to thrive in multicultural environments
  • Interdisciplinary collaboration skills
  • Knowledge of organic chemistry
  • Experience with solid-phase synthesis (plus)
  • High-throughput methods or automation experience (plus)
  • Proactive and problem-solving attitude
  • Interest in laboratory automation and workflows
  • Excellent organizational and multitasking skills
  • Fluency in English
  • Ambitious and collaborative nature
  • Mandatory internship certificate for non-EU/EFTA

Tasks

  • Develop novel solid-supported reaction protocols
  • Create library synthesis workflows
  • Work between Medicinal Chemistry and Lead Discovery
  • Design and implement automated workflows
  • Perform multi-step organic syntheses
  • Optimize reaction conditions on solid support
  • Characterize small molecule conjugates using LC-MS
  • Purify libraries using HPLC and Mass Spectrometry
  • Document research results in electronic laboratory notebooks
  • Present findings to cross-functional teams
  • Learn the drug discovery process from hit to lead

Education

  • Currently in higher education

Languages

  • EnglishBusiness Fluent

Tools & Technologies

  • solid-phase synthesis
  • high-throughput methods
  • automation
  • workflow design
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