Your personal AI career agent
Intern In Vitro Brain Distribution of Biologics(m/w/x)
Generating experimental data for biologics in neurosciences, establishing in vitro assays for antibody uptake and transcytosis. Mammalian cell culture and blood-brain barrier model experience required. Personal expression encouraged, open dialogue fostered.
Requirements
- Master’s or PhD program enrollment or degree completed within 12 months of start date, preferably in biochemistry, pharmacology, or molecular biology
- Eagerness to start career in pharmaceutical industry
- Hands-on experience with mammalian cell culture techniques
- Experience with primary or established blood-brain barrier models (e.g., transwell setups)
- Technical skills in cell engineering (plasmid transfection, viral transduction)
- Generation of engineered reporter cell lines
- Execution of fluorescence and luminescence-based in vitro assays
- Basic data analysis and experimental reporting
- Interest in translational science and drug delivery systems
- Fundamental understanding of pharmacokinetics
- Innovative problem-solving skills
- Strong communication skills
- English proficiency
- Ability to work independently with minimal supervision
- Teamwork skills
- Non-EU/Non-EFTA citizens: university confirmation of mandatory internship
- Non-EU/Non-EFTA citizens: continuous enrollment in university or PhD program for internship duration
Tasks
- Generate experimental data for biologics in neurosciences
- Establish in vitro assay for antibody uptake and transcytosis
- Study antibody recycling to understand PK properties
- Develop in vitro-in vivo correlation (IVIVC)
- Collaborate in multi-disciplinary team
- Gain hands-on experience with advanced methodologies
- Work with in vitro cellular models and bioluminescence assays
- Conduct transwell assays and microscopy techniques
- Develop and optimize in vitro models like BBB transwell systems
- Support drug development with quantitative kinetic methodologies
- Evaluate real-time cellular target engagement
- Use advanced split-luciferase technology
- Analyse and document experimental results
- Maintain high scientific standards in documentation
Education
- Vocational certificationOR
- Currently in higher education
Languages
- English – Business Fluent
Tools & Technologies
- mammalian cell culture
- transwell setups
- plasmid transfection
- viral transduction
- fluorescence assays
- luminescence assays
Benefits
Informal Culture
- Personal expression encouraged
- Open dialogue fostered
- Genuine connections valued
- Accepted and respected
Mentorship & Coaching
- Personal and professional thriving
Like this job?
BetaYour Career Agent finds similar jobs for you every day.
Not a perfect match?
- F. Hoffmann-La Roche AGFull-timeInternshipOn-siteBasel
- Roche
PhD Internship/RiSE(m/w/x)
Full-timeInternshipOn-siteBasel - Roche
M.Sc. Internship - in vitro Human Model Systems(m/w/x)
Full-timeInternshipOn-siteBasel - F. Hoffmann-La Roche AG
RiSE Internship - Targeting CNS Meninges(m/w/x)
Full-timeInternshipOn-siteBasel - F. Hoffmann-La Roche AG
Master Student Internship in Bioanalytics and Biomarkers(m/w/x)
Full-timeInternshipOn-siteBasel
Intern In Vitro Brain Distribution of Biologics(m/w/x)
Generating experimental data for biologics in neurosciences, establishing in vitro assays for antibody uptake and transcytosis. Mammalian cell culture and blood-brain barrier model experience required. Personal expression encouraged, open dialogue fostered.
Requirements
- Master’s or PhD program enrollment or degree completed within 12 months of start date, preferably in biochemistry, pharmacology, or molecular biology
- Eagerness to start career in pharmaceutical industry
- Hands-on experience with mammalian cell culture techniques
- Experience with primary or established blood-brain barrier models (e.g., transwell setups)
- Technical skills in cell engineering (plasmid transfection, viral transduction)
- Generation of engineered reporter cell lines
- Execution of fluorescence and luminescence-based in vitro assays
- Basic data analysis and experimental reporting
- Interest in translational science and drug delivery systems
- Fundamental understanding of pharmacokinetics
- Innovative problem-solving skills
- Strong communication skills
- English proficiency
- Ability to work independently with minimal supervision
- Teamwork skills
- Non-EU/Non-EFTA citizens: university confirmation of mandatory internship
- Non-EU/Non-EFTA citizens: continuous enrollment in university or PhD program for internship duration
Tasks
- Generate experimental data for biologics in neurosciences
- Establish in vitro assay for antibody uptake and transcytosis
- Study antibody recycling to understand PK properties
- Develop in vitro-in vivo correlation (IVIVC)
- Collaborate in multi-disciplinary team
- Gain hands-on experience with advanced methodologies
- Work with in vitro cellular models and bioluminescence assays
- Conduct transwell assays and microscopy techniques
- Develop and optimize in vitro models like BBB transwell systems
- Support drug development with quantitative kinetic methodologies
- Evaluate real-time cellular target engagement
- Use advanced split-luciferase technology
- Analyse and document experimental results
- Maintain high scientific standards in documentation
Education
- Vocational certificationOR
- Currently in higher education
Languages
- English – Business Fluent
Tools & Technologies
- mammalian cell culture
- transwell setups
- plasmid transfection
- viral transduction
- fluorescence assays
- luminescence assays
Benefits
Informal Culture
- Personal expression encouraged
- Open dialogue fostered
- Genuine connections valued
- Accepted and respected
Mentorship & Coaching
- Personal and professional thriving
Like this job?
BetaYour Career Agent finds similar jobs for you every day.
About the Company
Roche
Industry
Pharmaceuticals
Description
The company is dedicated to advancing science and ensuring access to healthcare for everyone.
Not a perfect match?
- F. Hoffmann-La Roche AG
Internship, Multimodal Bioimage Analysis (6-12 months)(m/w/x)
Full-timeInternshipOn-siteBasel - Roche
PhD Internship/RiSE(m/w/x)
Full-timeInternshipOn-siteBasel - Roche
M.Sc. Internship - in vitro Human Model Systems(m/w/x)
Full-timeInternshipOn-siteBasel - F. Hoffmann-La Roche AG
RiSE Internship - Targeting CNS Meninges(m/w/x)
Full-timeInternshipOn-siteBasel - F. Hoffmann-La Roche AG
Master Student Internship in Bioanalytics and Biomarkers(m/w/x)
Full-timeInternshipOn-siteBasel