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DMPK Lead(m/w/x)
Implementing AI-first strategies for drug discovery at biotech firm applying frontier AI, analyzing PD/toxicological data. PhD in Pharmaceutical Science or Chemistry, plus developing DMPK/quantitative pharmacology packages required. Work with frontier AI for deeper scientific insights.
Requirements
- PhD in Pharmaceutical Science, Pharmacy, Chemistry, or relevant subject
- 3+ years' professional experience as DMPK Lead
- Experience developing DMPK and quantitative pharmacology packages
- Experience partnering with Preclinical and Clinical teams
- In depth knowledge of biotransformation
- In depth knowledge of PK modelling
- Experience with biologics, peptides and new modalities
- Advanced knowledge of PKPD modelling
- Good understanding of machine learning techniques
- Familiarity with Python and KNIME
Tasks
- Design and implement AI-first DMPK strategies
- Integrate quantitative pharmacology into project strategies
- Design screening cascades and mechanistic experiments
- Analyze DMPK, PD, and toxicological data
- Predict clinical doses and safety windows
- Define Quantitative Pharmacology strategies with Pharmacology Leads
- Leverage company datasets to solve DMPK questions
- Optimize molecule design with Chemistry Leads
- Maintain expertise in human PK prediction methods
- Author DMPK sections for regulatory documents
- Promote inclusion and continuous professional development
Work Experience
- 3 years
Education
- Doctoral / PhD
Languages
- English – Business Fluent
Tools & Technologies
- Python
- KNIME
- Machine learning techniques
Benefits
Other Benefits
- Disability accommodation
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DMPK Lead(m/w/x)
Implementing AI-first strategies for drug discovery at biotech firm applying frontier AI, analyzing PD/toxicological data. PhD in Pharmaceutical Science or Chemistry, plus developing DMPK/quantitative pharmacology packages required. Work with frontier AI for deeper scientific insights.
Requirements
- PhD in Pharmaceutical Science, Pharmacy, Chemistry, or relevant subject
- 3+ years' professional experience as DMPK Lead
- Experience developing DMPK and quantitative pharmacology packages
- Experience partnering with Preclinical and Clinical teams
- In depth knowledge of biotransformation
- In depth knowledge of PK modelling
- Experience with biologics, peptides and new modalities
- Advanced knowledge of PKPD modelling
- Good understanding of machine learning techniques
- Familiarity with Python and KNIME
Tasks
- Design and implement AI-first DMPK strategies
- Integrate quantitative pharmacology into project strategies
- Design screening cascades and mechanistic experiments
- Analyze DMPK, PD, and toxicological data
- Predict clinical doses and safety windows
- Define Quantitative Pharmacology strategies with Pharmacology Leads
- Leverage company datasets to solve DMPK questions
- Optimize molecule design with Chemistry Leads
- Maintain expertise in human PK prediction methods
- Author DMPK sections for regulatory documents
- Promote inclusion and continuous professional development
Work Experience
- 3 years
Education
- Doctoral / PhD
Languages
- English – Business Fluent
Tools & Technologies
- Python
- KNIME
- Machine learning techniques
Benefits
Other Benefits
- Disability accommodation
Like this job?
BetaYour Career Agent finds similar jobs for you every day.
About the Company
Isomorphic Labs
Industry
Pharmaceuticals
Description
The company is applying frontier AI to unlock deeper scientific insights and accelerate drug discovery.
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