Novartis Pharma AG
Translational Medicine Academy fellow for Pharmacokinetics Sciences Modeling & Simulaton(m/w/x)
Vollzeitnur vor OrtKeine Angabe
Basel
Neuer Job?Nejo!
Dein persönlicher KI-Karriere-Agent
RORoche
Modelling and Simulations Scientist(m/w/x)
Basel
VollzeitVor OrtSenior
AI/ML
Data Science
Nejo KI-Zusammenfassung
Developing multi-scale PK, efficacy, and toxicology models for drug discovery. PhD-level degree in STEM and extensive mechanistic modeling experience required. Integration of experimental data from in vitro, in vivo, and omics studies.
Anforderungen
- PhD-level degree in natural sciences, mathematics, physical sciences, or engineering
- Advanced programming skills in R and Python, coding quickly and with high rigor
- Extensive experience in mechanistic modeling
- Strong mathematical foundation applied to drug discovery
- Ability to put complex results into drug development perspective
- Independent thinker with high creativity
- Track record of scientific excellence
- Strong lead author publication history
- Effective scientific communication skills
- Inclusive mindset
- Effective interaction with pharmacology scientists, project leaders, and collaborators
- Growth mindset with curiosity
- Willingness to learn and go beyond standard solutions
- Willingness to speak up and bring different perspectives
- Ability to lead consultants or outside collaborators effectively
- Proactive attitude with initiative
- Proposes solutions and maintains a "can-do" approach
- Independent thinker with scientific excellence track record
- Strong lead author publication history
Aufgaben
- Develop multi-scale models for PK, efficacy, and toxicology
- Integrate experimental data from in vitro, in vivo, and omics studies
- Build complex quantitative systems pharmacology (QSP) models
- Predict drug disposition and target attainment using mechanistic tumor-site interaction models
- Characterize drug accumulation and PK/PD relationships
- Extend modeling frameworks to combination therapies and antibody drug conjugates
- Design and deploy interactive tools using R and Shiny applications
- Leverage AI and Machine Learning for enhanced predictive accuracy
- Automate data integration and explore high-dimensional biological datasets
- Perform rigorous parameter estimation using Bayesian methods
- Communicate results to project teams and senior management
- Ensure M&S activities align with project goals and Roche standards
Berufserfahrung
- ca. 4 - 6 Jahre
Ausbildung
- Doktor / Ph.D.
Sprachen
- Englisch – verhandlungssicher
Tools & Technologien
- R
- Python
Die Originalanzeige dieses Stellenangebotes in der aktuellsten Version findest du hier. Nejo hat diesen Job automatisch von der Website des Unternehmens Roche erfasst und die Informationen auf Nejo mit Hilfe von KI für dich aufbereitet. Trotz sorgfältiger Analyse können einzelne Informationen unvollständig oder ungenau sein. Bitte prüfe immer alle Angaben in der Originalanzeige! Inhalte und Urheberrechte der Originalanzeige liegen beim ausschreibenden Unternehmen.
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Developing multi-scale PK, efficacy, and toxicology models for drug discovery. PhD-level degree in STEM and extensive mechanistic modeling experience required. Integration of experimental data from in vitro, in vivo, and omics studies.
Anforderungen
- PhD-level degree in natural sciences, mathematics, physical sciences, or engineering
- Advanced programming skills in R and Python, coding quickly and with high rigor
- Extensive experience in mechanistic modeling
- Strong mathematical foundation applied to drug discovery
- Ability to put complex results into drug development perspective
- Independent thinker with high creativity
- Track record of scientific excellence
- Strong lead author publication history
- Effective scientific communication skills
- Inclusive mindset
- Effective interaction with pharmacology scientists, project leaders, and collaborators
- Growth mindset with curiosity
- Willingness to learn and go beyond standard solutions
- Willingness to speak up and bring different perspectives
- Ability to lead consultants or outside collaborators effectively
- Proactive attitude with initiative
- Proposes solutions and maintains a "can-do" approach
- Independent thinker with scientific excellence track record
- Strong lead author publication history
Aufgaben
- Develop multi-scale models for PK, efficacy, and toxicology
- Integrate experimental data from in vitro, in vivo, and omics studies
- Build complex quantitative systems pharmacology (QSP) models
- Predict drug disposition and target attainment using mechanistic tumor-site interaction models
- Characterize drug accumulation and PK/PD relationships
- Extend modeling frameworks to combination therapies and antibody drug conjugates
- Design and deploy interactive tools using R and Shiny applications
- Leverage AI and Machine Learning for enhanced predictive accuracy
- Automate data integration and explore high-dimensional biological datasets
- Perform rigorous parameter estimation using Bayesian methods
- Communicate results to project teams and senior management
- Ensure M&S activities align with project goals and Roche standards
Berufserfahrung
- ca. 4 - 6 Jahre
Ausbildung
- Doktor / Ph.D.
Sprachen
- Englisch – verhandlungssicher
Tools & Technologien
- R
- Python
Die Originalanzeige dieses Stellenangebotes in der aktuellsten Version findest du hier. Nejo hat diesen Job automatisch von der Website des Unternehmens Roche erfasst und die Informationen auf Nejo mit Hilfe von KI für dich aufbereitet. Trotz sorgfältiger Analyse können einzelne Informationen unvollständig oder ungenau sein. Bitte prüfe immer alle Angaben in der Originalanzeige! Inhalte und Urheberrechte der Originalanzeige liegen beim ausschreibenden Unternehmen.
Gefällt dir diese Stelle?
BetaDein Career Agent findet täglich ähnliche Jobs für dich.
Über das Unternehmen
Roche
Branche
Pharmaceuticals
Beschreibung
The company is dedicated to advancing science and ensuring access to healthcare for everyone.
Noch nicht perfekt?
- Novartis Pharma AG
Translational Medicine Academy fellow for Pharmacokinetics Sciences Modeling & Simulaton(m/w/x)
Vollzeitnur vor OrtKeine AngabeBasel - Novartis Pharma AG
Translational Medicine Academy fellow for Pharmacokinetics Sciences Modeling & Simulaton(m/w/x)
Vollzeitnur vor OrtKeine AngabeBasel - Roche
DMPK-PD Project Leader(m/w/x)
Vollzeitnur vor OrtSeniorBasel - Novartis Pharma AG
Senior Expert - Science & Technology Upstream Process Modeling & Simulation(m/w/x)
Vollzeitnur vor OrtSeniorBasel - 1201 F. Hoffmann-La Roche AG
Senior / Principal Cheminformatics Scientist(m/w/x)
Vollzeitnur vor OrtSeniorBasel