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CSCSL Behring

Director, Non-clinical Pharmacology CVR(m/w/x)

Schlieren
Full-timeOn-siteSenior

Defining nonclinical pharmacology strategy for biotherapeutics in immunological, hematological, and cardiovascular disease areas. Overseeing in vivo efficacy and pharmacodynamic studies. Ph.D. in Pharmacology or related field and 10+ years nonclinical pharmacology experience in pharma/biotech required. Global project scope.

Requirements

  • Ph.D. in Pharmacology, Physiology, Biomedical Sciences, or related field
  • 10+ years of experience in nonclinical pharmacology within pharmaceutical or biotech industry or academic background
  • Strong expertise in in vivo pharmacology, disease models, and translational science
  • Familiarity with regulatory expectations for nonclinical pharmacology data
  • Proven ability to manage multiple projects and timelines
  • Strategic thinker with excellent problem-solving, communication, and interpersonal skills
  • Experience across multiple therapeutic areas and modalities is highly desirable
  • Extensive knowledge in Cardiovascular or Renal Biology; both viewed highly favorably

Tasks

  • Define and lead nonclinical pharmacology strategy
  • Design and oversee in vivo efficacy studies
  • Conduct pharmacodynamic and mechanism-of-action studies
  • Guide selection and validation of disease models
  • Develop and implement study protocols for pharmacology
  • Evaluate target engagement and biomarker studies
  • Select and collaborate with external partners or CROs
  • Ensure timely execution of pharmacology studies
  • Analyze and interpret complex data sets
  • Act as Senior Pharmacology lead on TA teams
  • Integrate pharmacology data with PK and Toxicology
  • Provide expert input on pharmacology-related issues
  • Contribute to due diligence for in-licensing opportunities
  • Prepare study reports and regulatory documents
  • Present findings to stakeholders and collaborators
  • Lead and mentor a team of Principal and Senior scientists
  • Foster a culture of scientific excellence and innovation

Work Experience

  • 10 years

Education

  • Doctoral / PhD

Languages

  • EnglishBusiness Fluent
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