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Director, Mechanistic Pharmacology(m/w/x)
Leading a Translational Research Pharmacology Lab for human blood plasma therapies in Hematology & CVR, collaborating with Data Science. PhD/MD/PhD in Life Sciences and 10+ years pharma/biotech R&D leadership experience required. Strategic role within a global network of plasma donation centers.
Requirements
- PhD or MD/PhD in Life Sciences with focus on Hematology, Cardio-vascular or Renal diseases, or related field
- Minimum of 10 years of experience in pharmaceutical or biotech R&D
- Proven leadership experience in managing scientific teams and laboratory staff
- Excellent communication, analytical, and interpersonal skills
- Demonstrated ability to drive innovation and manage complex projects
- High integrity, organizational skills, and a proactive, entrepreneurial mindset
Tasks
- Lead and develop the Translational Research Pharmacology Lab unit for Hematology & CVR in Zürich, Schlieren
- Define and implement translational research strategies aligned with global therapeutic area and platform priorities
- Collaborate closely with Data Science and Clinical Bioanalytics, Immunogenicity & Biomarker teams
- Represent Translational Research in Therapeutic Area Research Strategy Teams and contribute to strategic planning
- Define and implement an externalization strategy while monitoring the CRO landscape
- Build and maintain a network of external partners
- Supervise, mentor, and develop scientists and technicians, fostering a culture of innovation and collaboration
- Oversee recruitment, onboarding, and career development of team members
- Promote high standards in health, safety, and environment, ensuring compliance with quality and regulatory requirements
- Ensure scientific coordination and resource allocation across global research projects
- Lead the delivery of preclinical science and biomarker strategies to support clinical development
- Manage budgets, CAPEX investments, and operational planning for the Pharmacology Lab Unit
- Drive excellence in Stage 0 and Stage Gate 1 projects and contribute to new product opportunity evaluations
- Provide scientific input across R&D programs, including drug discovery and in vitro pharmacology
- Develop and execute assays to understand the mechanism of action of drug candidates
- Compile scientific reports, regulatory documents, and peer-reviewed publications
- Present research findings at internal and external meetings
- Maintain state-of-the-art knowledge through literature and congress participation
- Establish and maintain collaborations with academic institutions, biotech companies, and CROs
- Drive and execute wet Due Diligence activities in collaboration with external partners
- Support patent filings and legal contract negotiations with legal and IP departments
Work Experience
- 10 years
Education
- Doctoral / PhD
Languages
- English – Business Fluent
- German – Basic
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Director, Mechanistic Pharmacology(m/w/x)
Leading a Translational Research Pharmacology Lab for human blood plasma therapies in Hematology & CVR, collaborating with Data Science. PhD/MD/PhD in Life Sciences and 10+ years pharma/biotech R&D leadership experience required. Strategic role within a global network of plasma donation centers.
Requirements
- PhD or MD/PhD in Life Sciences with focus on Hematology, Cardio-vascular or Renal diseases, or related field
- Minimum of 10 years of experience in pharmaceutical or biotech R&D
- Proven leadership experience in managing scientific teams and laboratory staff
- Excellent communication, analytical, and interpersonal skills
- Demonstrated ability to drive innovation and manage complex projects
- High integrity, organizational skills, and a proactive, entrepreneurial mindset
Tasks
- Lead and develop the Translational Research Pharmacology Lab unit for Hematology & CVR in Zürich, Schlieren
- Define and implement translational research strategies aligned with global therapeutic area and platform priorities
- Collaborate closely with Data Science and Clinical Bioanalytics, Immunogenicity & Biomarker teams
- Represent Translational Research in Therapeutic Area Research Strategy Teams and contribute to strategic planning
- Define and implement an externalization strategy while monitoring the CRO landscape
- Build and maintain a network of external partners
- Supervise, mentor, and develop scientists and technicians, fostering a culture of innovation and collaboration
- Oversee recruitment, onboarding, and career development of team members
- Promote high standards in health, safety, and environment, ensuring compliance with quality and regulatory requirements
- Ensure scientific coordination and resource allocation across global research projects
- Lead the delivery of preclinical science and biomarker strategies to support clinical development
- Manage budgets, CAPEX investments, and operational planning for the Pharmacology Lab Unit
- Drive excellence in Stage 0 and Stage Gate 1 projects and contribute to new product opportunity evaluations
- Provide scientific input across R&D programs, including drug discovery and in vitro pharmacology
- Develop and execute assays to understand the mechanism of action of drug candidates
- Compile scientific reports, regulatory documents, and peer-reviewed publications
- Present research findings at internal and external meetings
- Maintain state-of-the-art knowledge through literature and congress participation
- Establish and maintain collaborations with academic institutions, biotech companies, and CROs
- Drive and execute wet Due Diligence activities in collaboration with external partners
- Support patent filings and legal contract negotiations with legal and IP departments
Work Experience
- 10 years
Education
- Doctoral / PhD
Languages
- English – Business Fluent
- German – Basic
About the Company
CSL Plasma
Industry
Pharmaceuticals
Description
Das Unternehmen betreibt eines der weltweit größten Netzwerke von Spendezentren für menschliches Blutplasma und stellt lebensrettende Therapien her.
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