Sanofi-Aventis Deutschland GmbH
Translational T1/17 Immunology Lead(m/w/x)
Full-timeOn-siteSenior
Frankfurt am Main
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SASanofi-Aventis Deutschland GmbH
Senior Scientist - Transgenic Technology and Model Characterization(m/w/x)
Frankfurt am Main
Full-timeOn-siteSenior
Nejo AI Summary
Designing and validating genetically modified rodent models for biopharma R&D. Advanced multicolor spectral flow cytometry and unsupervised analysis expertise required. 14 weeks' gender-neutral parental leave.
Requirements
- PhD in immunology, molecular biology, mouse genetics, or related biological sciences
- Minimum 5 years hands-on experience in multicolor spectral flow cytometry (minimum 15 colors), including panel design, optimization, analysis, and critical interpretation
- Extensive experience with spectral cytometers (Cytek, BD, Sony, or similar platforms)
- Proven expertise in unsupervised flow cytometry analysis (OMIQ, FlowJo, or equivalent) - mandatory
- Demonstrated proficiency in statistical analysis using Prism - mandatory
- Strong background in mouse molecular genetics and immuno-phenotyping
- Experience in project management: designing, organizing, and executing experiments aligned with project objectives
- Expert-level knowledge in immunology and biological sciences
- Proficiency in culturing murine primary cells and performing cell isolation techniques
- Competency in mice experimentation (Designer level) including genotyping, breeding, and various injection routes
- Strong computer skills including Microsoft Office Suite (Word, PowerPoint, Excel) and database management systems
- English: Full professional proficiency required
- Excellent organizational and communication skills
- Ability to lead and work collaboratively within multidisciplinary teams
- Strong motivation to contribute to developing genetically modified preclinical animal models
- Proactive approach to implementing innovative procedures and methodologies
- Demonstrated ability to manage multiple projects and meet deadlines
- Detail-oriented with commitment to data quality and integrity
- Self-motivated with ability to work independently and as part of a team
- Strong problem-solving skills and scientific curiosity
- Commitment to continuous learning and professional development
Tasks
- Conduct molecular and immuno-phenotypic characterization of genetically modified rodent models
- Design, organize, and execute validation experiments for new transgenic models
- Collaborate with investigators and researchers to define project needs
- Perform advanced multicolor spectral flow cytometry, including panel design and optimization
- Interpret critical flow cytometry data
- Conduct unsupervised flow cytometry analysis using OMIQ and FlowJo
- Characterize diverse immune and non-immune cell sub-populations by cytometry
- Culture murine primary cells, including isolation, culture, activation, and differentiation
- Prepare comprehensive reports and presentations for stakeholders
- Ensure data quality and integrity through compilation and database entry
- Manage electronic laboratory notebooks and maintain documentation standards
- Apply statistical analysis methods using Prism and other software
- Maintain working relationships with model providers, CROs, and colleagues
- Provide expert guidance on transgenic research models
- Recommend optimal validation strategies
- Share knowledge through oral presentations and discussions
- Implement and recommend new procedures for model development
- Conduct mice experimentation: genotyping, breeding, injections, immunization, and sample processing
- Follow HSE requirements for laboratory activities
- Contribute to laboratory management and best practice development
Work Experience
- 5 years
Education
- Doctoral / PhD
Languages
- English – Business Fluent
Tools & Technologies
- Cytek
- BD
- Sony
- OMIQ
- FlowJo
- Prism
- Microsoft Office Suite
- Word
- PowerPoint
- Excel
Benefits
Healthcare & Fitness
- High-quality healthcare
- Prevention and wellness programs
Generous Parental Leave
- 14 weeks' gender-neutral parental leave
Find the original job posting in its most current version here. Nejo automatically captured this job from the website of Sanofi-Aventis Deutschland GmbH and processed the information on Nejo with the help of AI for you. Despite careful analysis, some information may be incomplete or inaccurate. Please always verify all details in the original posting! Content and copyrights of the original posting belong to the advertising company.
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SASanofi-Aventis Deutschland GmbH
Senior Scientist - Transgenic Technology and Model Characterization(m/w/x)
Frankfurt am Main
Full-timeOn-siteSenior
Nejo AI Summary
Designing and validating genetically modified rodent models for biopharma R&D. Advanced multicolor spectral flow cytometry and unsupervised analysis expertise required. 14 weeks' gender-neutral parental leave.
Requirements
- PhD in immunology, molecular biology, mouse genetics, or related biological sciences
- Minimum 5 years hands-on experience in multicolor spectral flow cytometry (minimum 15 colors), including panel design, optimization, analysis, and critical interpretation
- Extensive experience with spectral cytometers (Cytek, BD, Sony, or similar platforms)
- Proven expertise in unsupervised flow cytometry analysis (OMIQ, FlowJo, or equivalent) - mandatory
- Demonstrated proficiency in statistical analysis using Prism - mandatory
- Strong background in mouse molecular genetics and immuno-phenotyping
- Experience in project management: designing, organizing, and executing experiments aligned with project objectives
- Expert-level knowledge in immunology and biological sciences
- Proficiency in culturing murine primary cells and performing cell isolation techniques
- Competency in mice experimentation (Designer level) including genotyping, breeding, and various injection routes
- Strong computer skills including Microsoft Office Suite (Word, PowerPoint, Excel) and database management systems
- English: Full professional proficiency required
- Excellent organizational and communication skills
- Ability to lead and work collaboratively within multidisciplinary teams
- Strong motivation to contribute to developing genetically modified preclinical animal models
- Proactive approach to implementing innovative procedures and methodologies
- Demonstrated ability to manage multiple projects and meet deadlines
- Detail-oriented with commitment to data quality and integrity
- Self-motivated with ability to work independently and as part of a team
- Strong problem-solving skills and scientific curiosity
- Commitment to continuous learning and professional development
Tasks
- Conduct molecular and immuno-phenotypic characterization of genetically modified rodent models
- Design, organize, and execute validation experiments for new transgenic models
- Collaborate with investigators and researchers to define project needs
- Perform advanced multicolor spectral flow cytometry, including panel design and optimization
- Interpret critical flow cytometry data
- Conduct unsupervised flow cytometry analysis using OMIQ and FlowJo
- Characterize diverse immune and non-immune cell sub-populations by cytometry
- Culture murine primary cells, including isolation, culture, activation, and differentiation
- Prepare comprehensive reports and presentations for stakeholders
- Ensure data quality and integrity through compilation and database entry
- Manage electronic laboratory notebooks and maintain documentation standards
- Apply statistical analysis methods using Prism and other software
- Maintain working relationships with model providers, CROs, and colleagues
- Provide expert guidance on transgenic research models
- Recommend optimal validation strategies
- Share knowledge through oral presentations and discussions
- Implement and recommend new procedures for model development
- Conduct mice experimentation: genotyping, breeding, injections, immunization, and sample processing
- Follow HSE requirements for laboratory activities
- Contribute to laboratory management and best practice development
Work Experience
- 5 years
Education
- Doctoral / PhD
Languages
- English – Business Fluent
Tools & Technologies
- Cytek
- BD
- Sony
- OMIQ
- FlowJo
- Prism
- Microsoft Office Suite
- Word
- PowerPoint
- Excel
Benefits
Healthcare & Fitness
- High-quality healthcare
- Prevention and wellness programs
Generous Parental Leave
- 14 weeks' gender-neutral parental leave
Find the original job posting in its most current version here. Nejo automatically captured this job from the website of Sanofi-Aventis Deutschland GmbH and processed the information on Nejo with the help of AI for you. Despite careful analysis, some information may be incomplete or inaccurate. Please always verify all details in the original posting! Content and copyrights of the original posting belong to the advertising company.
About the Company
Sanofi-Aventis Deutschland GmbH
Industry
Pharmaceuticals
Description
Das Unternehmen bietet Arzneimittel zur Prävention von Herz-Kreislauf-Erkrankungen an und setzt sich für die Verbesserung der Lebensqualität ein.
Not a perfect match?
- Sanofi-Aventis Deutschland GmbH
Translational T1/17 Immunology Lead(m/w/x)
Full-timeOn-siteSeniorFrankfurt am Main - Sanofi
Scientist high-throughput Biophysical Characterization(m/w/x)
Full-timeOn-siteExperiencedFrankfurt am Main - Sanofi-Aventis Deutschland GmbH
Scientist - Tech Area(m/w/x)
Full-timeOn-siteSeniorFrankfurt am Main - Sanofi
Laborleiter:in IDD - In vitro Biologie(m/w/x)
Full-timeTemporary contractOn-siteSeniorFrankfurt am Main - Sanofi-Aventis Deutschland GmbH
Scientist Protein Analytics(m/w/x)
Full-timeOn-siteExperiencedFrankfurt am Main