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MEMerck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA

Senior Scientist, Preclinical Development in Animal Health with Focus on Immunology(m/w/x)

Schwabenheim an der Selz
Full-timeOn-siteSenior

Conducting GLP-compliant studies for animal health product R&D, evaluating immunology and monoclonal antibody characterization. Veterinary Medicine degree with PhD required. Focus on pharmacokinetics, metabolism, and toxicology evaluation.

Requirements

  • Veterinary Medicine degree, including PhD or comparable
  • R&D experience, ideally in international veterinary pharma
  • Animal study management experience, ideally GLP
  • Profound knowledge in pharmacology, metabolism, toxicology, immunology, and monoclonal antibody research
  • Pharmacokinetic, metabolic, immunogenic, and monoclonal antibody evaluation experience
  • Hands-on experience with immunological assays, vaccine efficacy, or monoclonal antibody characterization
  • Precise, analytical, and creative problem-solving approach
  • Fluent written and spoken English and German

Tasks

  • Support R&D for new and existing animal health products
  • Compile and assess compound profiles through literature and experiments
  • Plan and conduct GLP-compliant studies
  • Evaluate toxicology, target animal safety, pharmacokinetics, metabolism, residue depletion, immunogenicity, and monoclonal antibody characterization
  • Design and oversee immunology and monoclonal antibody studies
  • Characterize antigens and conduct immune response assays
  • Test antibody efficacy
  • Compile expert reports and regulatory submissions
  • Prepare scientific presentations for authorities and internal stakeholders
  • Maintain and expand contacts with contract research organizations
  • Collaborate with external experts and universities
  • Represent preclinical development in international project teams

Work Experience

  • approx. 4 - 6 years

Education

  • Bachelor's degree

Languages

  • EnglishFluent
  • GermanFluent

Tools & Technologies

  • ADME
  • Biochemical Assays
  • Cell-Based Assays
  • Drug Metabolism
  • ELISA
  • Flow Cytometry
  • High Resolution Mass Spectrometry (HRMS)
  • Ligand Binding Assay
  • Liquid Chromatography-Mass Spectrometry (LC-MS)
  • Mass Spectrometry Analysis
  • Metabolite Identification
  • Pharmacodynamics
  • Pharmacokinetics
  • Pharmacotherapeutics
  • Vaccine Efficacy Studies
  • Monoclonal Antibody Characterization
Find the original job posting in its most current version here. Nejo automatically captured this job from the website of Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA and processed the information on Nejo with the help of AI for you. Despite careful analysis, some information may be incomplete or inaccurate. Please always verify all details in the original posting! Content and copyrights of the original posting belong to the advertising company.

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