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BA
Bayer
18d ago

Senior Principal Scientist siRNA(m/w/x)

Wuppertal
Full-timeWith Home OfficeSenior

Description

In this role, you will be at the forefront of siRNA drug discovery, leading interdisciplinary teams and driving innovative projects. Your expertise will guide the integration of siRNA into therapeutic development, ensuring alignment with organizational goals and fostering collaboration across various teams.

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Requirements

  • •Ph.D. in Biochemistry, Chemistry, Molecular Biology, Pharmacology, or related field
  • •Significant experience in post-doctoral or industry setting in drug discovery
  • •Strong focus on siRNA research, including designing siRNA molecules and optimising delivery methods
  • •Experience with antisense oligonucleotides
  • •Extensive knowledge of siRNA and siRNA conjugate biology and technology
  • •Deep knowledge of siRNA company landscapes and CRO networks
  • •Ability to integrate genomics and bioinformatics into work
  • •Proven track record in targeted siRNA related drug discovery or development
  • •Experience in taking scientific ideas from concept to validation
  • •Evidence of innovation in past projects
  • •Drug-hunter mindset
  • •Strong ability to lead interdisciplinary teams
  • •Proficient in matrix leadership and project management
  • •Mentorship experience
  • •Ability to align scientific goals with portfolio and business priorities
  • •Experience in evaluating project success and making data-driven recommendations
  • •Contribution to portfolio strategy
  • •Demonstrated Visionary, Architect, Coach, and Catalyst leadership behaviours
  • •Ability to foresee trends and drive change
  • •Confidence in handling ambiguity and complexity
  • •Excellent communication skills
  • •Strong presentation and intercultural communication skills
  • •Fluency in English
  • •Proficiency in German

Education

Doctoral / PhD

Work Experience

approx. 4 - 6 years

Tasks

  • •Drive project discussions to enhance R&D productivity
  • •Act as the main expert on siRNA therapeutics in R&D
  • •Provide guidance on siRNA design and delivery best practices
  • •Integrate siRNA into drug discovery with diverse teams
  • •Guide teams on assay design and delivery technologies
  • •Lead interdisciplinary teams in siRNA drug discovery
  • •Plan and execute complex studies and interpret results
  • •Present findings to senior management as needed
  • •Provide strategic direction for siRNA projects
  • •Ensure alignment with organizational goals during portfolio reviews
  • •Manage external collaborations with partner companies and CROs
  • •Coordinate efforts to advance RNA therapeutics
  • •Collaborate with RED teams in Cardiovascular/Renal and Oncology
  • •Align siRNA work with development needs
  • •Mentor junior scientists and colleagues in RNA therapeutics
  • •Enhance internal siRNA research capabilities
  • •Develop infrastructure and methods for siRNA research
  • •Evaluate new technologies for potential collaboration
  • •Initiate new research in siRNA and tissue targeting
  • •Identify opportunities for novel therapeutic approaches
  • •Lead innovative projects from concept to proof-of-concept
  • •Inspire bold ideas and design strategies in R&D

Languages

English – Native

German – Basic

Benefits

Competitive Pay

  • •Competitive compensation package
  • •Global equity-based cash plan

Bonuses & Incentives

  • •Performance-based company bonus

Flexible Working

  • •Flexible work arrangements

Childcare

  • •Company daycare centers
  • •Childcare support
  • •Summer camps for children

Family Support

  • •Time off for family care

Learning & Development

  • •Learning and development opportunities
  • •Training programs

Mentorship & Coaching

  • •Coaching and mentoring programs

Healthcare & Fitness

  • •Free health checks
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