SUSONITY
.Scientist Structural Biophysics(m/w/x)
Full-timeOn-siteExperienced
Darmstadt
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SUSUSONITY
Principal Scientist Structural Biology(m/w/x)
Darmstadt
Full-timeOn-siteSenior
AI/ML
Nejo AI Summary
Elucidating structural mode of action for macromolecular complexes in Oncology, Neurology, and Fertility. Deep expertise in high-resolution cryo-EM structure determination required. End-to-end strategies for structural enablement, single-particle cryo-EM expansion.
Requirements
- PhD in Structural Biology or related field
- More than ten years relevant experience (biopharma/biotech)
- Strong track record designing, executing, driving complex structural biology projects
- Deep expertise in high-resolution cryo-EM structure determination
- Experience in cryo-EM sample generation, data collection, processing
- Experience in cryo-EM structure refinement with industry-standard software
- Experience with antigen–antibody complexes
- Experience with protein degrader complexes
- Deep understanding of structure–function relationships
- Preferable experience in protein crystallography
- Preferable experience in biophysical methods (HDX-MS, SAXS, Refeyn, FIDA, DSF)
- Experience with cloud-based/HPC data management and processing
- Experience with LINUX scripting
- Experience with AI/ML-based prediction of biomolecular structures
- Effective collaborator and leader in multidisciplinary settings
- Excellent English communication skills
- Skilled in guiding and mentoring scientists
- Skilled in coordinating multi-site work
- Skilled in managing CROs to balance project demands
- Proven ability to convey complex data clearly to drive decisions
- Strong publication history or impactful drug discovery contributions (oncology/immunology/neuroscience favored)
- Excellent problem-solving skills
- Experience introducing relevant new technologies
Tasks
- Provide scientific leadership in interdisciplinary projects
- Elucidate structural mode of action for macromolecular complexes
- Enable structure-based design for antibodies and molecular degraders
- Implement and expand single-particle cryo-EM capabilities
- Develop end-to-end strategies for structural enablement
- Coordinate CRO and collaboration-partner activities
- Drive innovations in structural biology
- Communicate scientific findings to cross-functional teams
- Influence informed and fast decision-making
- Mentor and develop junior scientists in structural biology
- Contribute to a high-performing, collaborative culture
Work Experience
- 10 years
Education
- Doctoral / PhD
Languages
- English – Business Fluent
Tools & Technologies
- cryo-EM
- HDX-MS
- SAXS
- Refeyn
- FIDA
- DSF
- HPC
- LINUX
- AI/ML
Find the original job posting in its most current version here. Nejo automatically captured this job from the website of SUSONITY and processed the information on Nejo with the help of AI for you. Despite careful analysis, some information may be incomplete or inaccurate. Please always verify all details in the original posting! Content and copyrights of the original posting belong to the advertising company.
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SUSUSONITY
Principal Scientist Structural Biology(m/w/x)
Darmstadt
Full-timeOn-siteSenior
AI/ML
Nejo AI Summary
Elucidating structural mode of action for macromolecular complexes in Oncology, Neurology, and Fertility. Deep expertise in high-resolution cryo-EM structure determination required. End-to-end strategies for structural enablement, single-particle cryo-EM expansion.
Requirements
- PhD in Structural Biology or related field
- More than ten years relevant experience (biopharma/biotech)
- Strong track record designing, executing, driving complex structural biology projects
- Deep expertise in high-resolution cryo-EM structure determination
- Experience in cryo-EM sample generation, data collection, processing
- Experience in cryo-EM structure refinement with industry-standard software
- Experience with antigen–antibody complexes
- Experience with protein degrader complexes
- Deep understanding of structure–function relationships
- Preferable experience in protein crystallography
- Preferable experience in biophysical methods (HDX-MS, SAXS, Refeyn, FIDA, DSF)
- Experience with cloud-based/HPC data management and processing
- Experience with LINUX scripting
- Experience with AI/ML-based prediction of biomolecular structures
- Effective collaborator and leader in multidisciplinary settings
- Excellent English communication skills
- Skilled in guiding and mentoring scientists
- Skilled in coordinating multi-site work
- Skilled in managing CROs to balance project demands
- Proven ability to convey complex data clearly to drive decisions
- Strong publication history or impactful drug discovery contributions (oncology/immunology/neuroscience favored)
- Excellent problem-solving skills
- Experience introducing relevant new technologies
Tasks
- Provide scientific leadership in interdisciplinary projects
- Elucidate structural mode of action for macromolecular complexes
- Enable structure-based design for antibodies and molecular degraders
- Implement and expand single-particle cryo-EM capabilities
- Develop end-to-end strategies for structural enablement
- Coordinate CRO and collaboration-partner activities
- Drive innovations in structural biology
- Communicate scientific findings to cross-functional teams
- Influence informed and fast decision-making
- Mentor and develop junior scientists in structural biology
- Contribute to a high-performing, collaborative culture
Work Experience
- 10 years
Education
- Doctoral / PhD
Languages
- English – Business Fluent
Tools & Technologies
- cryo-EM
- HDX-MS
- SAXS
- Refeyn
- FIDA
- DSF
- HPC
- LINUX
- AI/ML
Find the original job posting in its most current version here. Nejo automatically captured this job from the website of SUSONITY and processed the information on Nejo with the help of AI for you. Despite careful analysis, some information may be incomplete or inaccurate. Please always verify all details in the original posting! Content and copyrights of the original posting belong to the advertising company.
About the Company
SUSONITY
Industry
Healthcare
Description
Das Unternehmen entwickelt Medikamente, intelligente Geräte und innovative Technologien in Therapiegebieten wie der Onkologie, Neurologie und Fruchtbarkeit.
Not a perfect match?
- SUSONITY
.Scientist Structural Biophysics(m/w/x)
Full-timeOn-siteExperiencedDarmstadt - SUSONITY
Associate Director in Data Science, Digital Health Analytics and Innovation(m/w/x)
Full-timeOn-siteSeniorDarmstadt - SUSONITY
Director, Head of Inspection & TMF Center of Excellence(m/w/x)
Full-time/Part-timeOn-siteSeniorDarmstadt - DEU - 8800 Takeda Pharma Vertrieb GmbH & Co. KG
Senior Medical Scientific Liaison Manager Oncology Schwerpunkt Solide Tumore(m/w/x)
Full-timeOn-siteSeniorBerlin, Koblenz, Wiesbaden, Darmstadt, Mannheim, Heidelberg, Stuttgart, Freiburg im Breisgau - Focused Energy
Senior R&D Engineer (Mechatronics & Hardware)(m/w/x)
Full-timeOn-siteSeniorDarmstadt