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The German Cancer Research Center (DKFZ)
last mo.

Postdoctoral Researcher in Sex-Biased Cancer Development(m/w/x)

Heidelberg
Full-timeOn-siteExperienced
AI/ML

Description

In this postdoctoral role, you will explore the genomic mechanisms behind sex-biased cancer development, utilizing advanced model systems and cutting-edge technologies to uncover the complexities of tumorigenesis and organismal development.

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Requirements

  • Master’s degree (M.Sc.) and Ph.D. in molecular or cancer biology
  • Strong background in experimental design and execution
  • Strong track record of scientific communication
  • Strong track record of collaborative work
  • Proficiency in spoken and written English
  • Evidence of collaborativity, creativity, and leadership
  • Knowledge of large-scale sequencing technologies
  • Knowledge of spatial biology approaches and cutting-edge technologies
  • Experience operating with Linux and high-performance clusters
  • Experience with R/Python and Snakemake or Nextflow

Education

Doctoral / PhD

Work Experience

approx. 1 - 4 years

Tasks

  • Investigate genomic mechanisms of sex-biased cancer development
  • Utilize model systems to study sex chromosomes and hormones in cancer
  • Develop a controlled cancer induction system in mice using chemical carcinogenesis
  • Analyze large-scale patient cohorts to understand DNA lesion persistence
  • Examine how genetic background influences cancer evolution
  • Repurpose microfluidics technology to study early mitoses after mutagenesis
  • Conduct large-scale genetic analysis with experimental models
  • Apply spatial and single-cell sequencing technologies to study tumorigenesis
  • Identify and classify cellular populations and niches in cancer
  • Develop computational approaches, including AI/ML, to interpret genetic changes

Tools & Technologies

Linuxhigh-performance clustersRPythonSnakemakeNextflowlarge-scale sequencing technologiesspatial biology approaches

Languages

EnglishBusiness Fluent

Benefits

Flexible Working

  • Flexible working hours

Family Support

  • Possibility for part-time work
  • Family-friendly work environment

Retirement Plans

  • Company pension plan

More Vacation Days

  • 30 days vacation

Public Transport Subsidies

  • Discounted Germany job ticket

Healthcare & Fitness

  • Comprehensive health management

Other Benefits

  • Access to DKFZ International Postdoc Program

Career Advancement

  • Career service for personal development
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