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BABayer

Postdoc DMPK (in vitro ADME & IC) - Proteomics(m/w/x)

Wuppertal
Full-timeOn-site
Data Science

Supporting drug discovery projects with untargeted and targeted proteomics, including DIA, on Orbitrap instruments. Strong background in proteomics sample prep, data acquisition, and analysis required. Flexible work arrangements, language learning platform.

Requirements

  • PhD in life sciences (biology, protein biochemistry, analytical chemistry, or related field)
  • Strong background in untargeted (focus on DIA) and targeted proteomics
  • Proteomics sample preparation, data acquisition, and data analysis
  • Hands-on experience with nano LC and high-resolution mass spectrometry (preferably Orbitrap instruments)
  • Handling, annotating, and visualizing complex proteomics datasets
  • Automated sample preparation experience (advantageous)
  • Basic knowledge of drug metabolism and pharmacokinetics (advantageous)
  • Scientific rigor, efficiency, creativity, and organization
  • Collaborative mindset and teamwork in interdisciplinary settings
  • Clear and confident communication and presentation skills
  • Excellent English skills (spoken and written)

Tasks

  • Support research projects using proteomics methods
  • Address on- and off-target profiles
  • Determine target occupancy and targeted protein degradation
  • Establish and optimize new proteomics techniques
  • Improve existing proteomics workflows
  • Elucidate disease mechanisms
  • Characterize PK/PD and PK/TK relationships
  • Work with novel modalities like covalent binders
  • Implement multi-omics approaches in preclinical development
  • Support preclinical safety and toxicology studies
  • Evaluate and interpret preclinical study results

Education

  • Doctoral / PhD

Languages

  • EnglishBusiness Fluent

Tools & Technologies

  • Proteome Discoverer
  • Spectronaut
  • Skyline
  • R
  • Python

Benefits

Flexible Working

  • Flexible work arrangements

Learning & Development

  • Professional development opportunities
  • Learning opportunities
  • Language learning platform

Public Transport Subsidies

  • Job tickets for sustainable mobility

Corporate Discounts

  • Corporate Benefits program
  • Sales discounts from 150+ brands

Informal Culture

  • Inclusive work environment
Find the original job posting in its most current version here. Nejo automatically captured this job from the website of Bayer and processed the information on Nejo with the help of AI for you. Despite careful analysis, some information may be incomplete or inaccurate. Please always verify all details in the original posting! Content and copyrights of the original posting belong to the advertising company.

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