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UNUniversitätsklinikum Erlangen

Naturwissenschaftlicher Doktorand / PhD position “long-lived RNAs in motor neuron diseases”(m/w/x)

Erlangen
Part-timeOn-site

In this research role, you will investigate RNA metabolism in motor neuron diseases by combining advanced imaging techniques with the cultivation of complex brain organoids.

Requirements

  • Diploma, Master’s degree in Molecular Medicine, Biology, or related field
  • Proficiency in English
  • High motivation, intellectual curiosity, and research enthusiasm
  • Critical and independent thinking
  • Strong team spirit and collaboration willingness
  • Interest in neuroscience, stem cell biology, and neurodegeneration
  • Good experience in tissue culture
  • Desirable experience in hiPSC culture, differentiation, and brain organoids
  • Desirable experience with immunohistochemistry, microscopy, and image analysis
  • Desirable experience analyzing neuronal differentiation and cell death

Tasks

  • Culture and maintain patient-derived iPSCs
  • Manage control-derived iPSCs and brain organoids
  • Phenotype structural and functional neural deficits
  • Perform immunohistochemical analyses
  • Conduct RNA imaging using FISH and RNAscope
  • Execute electron microscopy on brain organoids
  • Analyze human post-mortem tissue

Education

Vocational certification

Languages

EnglishBusiness Fluent

Tools & Technologies

hiPSC culturebrain organoidsimmunohistochemistryfluorescence microscopyconfocal laser microscopyimage analysis

Benefits

Retirement Plans

  • Supplementary pension coverage (VBL)

Learning & Development

  • Structured onboarding and training
  • Advanced training opportunities

Healthcare & Fitness

  • Workplace health promotion program

Mentorship & Coaching

  • 3-year structured PhD program
  • Expert supervision and mentorship

Other Benefits

  • Interdisciplinary thesis research

Informal Culture

  • Collaborative scientific environment

Modern Office

  • State-of-the-art research facilities
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