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FRFraunhofer-Gesellschaft

Master's Thesis in Cell Biology and Extracellular Vesicles(m/w/x)

Rostock
Full-timeInternshipOn-site

Investigating renal membrane transporters and extracellular vesicles using 2D/3D cell culture models. Basic lab techniques and sterile cell culture required. Access to state-of-the-art technology, creative research freedom.

Requirements

  • Bachelor’s degree (B.Sc.) in life sciences or current Master’s enrollment
  • Basic laboratory techniques (pipetting, sterile cell culture)
  • Experience in biological or chemical laboratory environment (desirable)
  • Knowledge of data analysis and processing
  • Enjoyment of learning new practical skills
  • Curiosity and structure in approaching unfamiliar topics
  • Analytical thinking and quick grasp of topics

Tasks

  • Conduct literature research on renal membrane transporters and extracellular vesicles
  • Establish and cultivate RPTEC/TERT1 cells in 2D and 3D cell culture models
  • Investigate strategies to increase OAT1/3 expression in cells
  • Analyze cell status using microscopic methods and determine cell viability
  • Evaluate OAT1/3 expression and localization with immunofluorescence microscopy and Western blot
  • Explore strategies influencing EV release
  • Isolate EVs from cell culture supernatants
  • Characterize EVs by size, concentration, and composition
  • Perform functional assays to analyze transporter-dependent transport processes
  • Evaluate and interpret research results

Education

  • Currently in higher educationOR
  • Bachelor's degree

Languages

  • EnglishBusiness Fluent

Tools & Technologies

  • common software tools

Benefits

Diverse Work

  • Exciting research topic

Mentorship & Coaching

  • Intensive academic supervision
  • Expert supervision

Informal Culture

  • Creative research freedom

Purpose-Driven Work

  • Societal relevance
  • High degree of autonomy

Modern Equipment

  • Access to state-of-the-art technology

Other Benefits

  • Valuable practical experience
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