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Senior Scientist Mass Spectrometry(m/w/x)
Biomolecule characterization using LC-MS for rare disease therapies. 3+ years biopharmaceutical industry experience required. Well-being support, training team members on advanced techniques.
Requirements
- Postgraduate degree (preferably PhD) in biological sciences, biophysics, or analytical chemistry
- 3+ years biopharmaceutical industry experience in biomolecule characterization by LC-MS
- Experience in LC-MS method development, optimization, and qualification using QbD principles
- Advanced expertise in LC-MS bioanalytics for protein/peptide characterization, especially high-resolution MS (e.g., Orbitrap)
- Strong experience with peptide mapping, intact/subunit mass analysis, and MAM
- In-depth knowledge of PTM analysis (glycosylation, deamidation, oxidation, C-terminal variants)
- Expertise in data evaluation, interpretation, and reporting of complex LC-MS datasets
- Experience with additional bioanalytical workflows, particularly LC separation techniques (RP-LC, SEC, IEX, CE) is a strong plus
- Hands-on experience and knowledge in instrument operation and maintenance
- Good understanding of scientific process, including hypothesis development and experimental design (DoE)
- Strong expertise in biomolecule characterization using LC-MS approaches
- Advanced technical knowledge of mass spectrometry techniques and analytical assay development
- Ability to interpret complex analytical datasets and support scientific decision-making
- Strong scientific problem-solving and troubleshooting skills
- Ability to work independently and collaboratively in interdisciplinary and cross-functional teams
- Strong organizational, documentation, and reporting skills
- Scientific enthusiasm, creativity, and hands-on laboratory mindset
- Proficient English verbal and written communication skills
- Ability to provide technical support, guidance, and training to other scientists and team members
Tasks
- Apply technical background in biomolecule characterization using LC-MS
- Develop fit-for-purpose analytical assays
- Direct workflows and provide technical support
- Train team members on advanced techniques
- Contribute to translating innovative platforms into automated methods
- Design and perform MS-based experiments
- Interpret results to support product characterization
- Develop and implement novel analytical methods
- Ensure methods meet quality by design principles
- Qualify methods according to project and product demands
- Act as Subject Matter Expert for mass spectrometry
- Provide scientific leadership and guidance
- Evaluate and implement new technologies
- Manage resources effectively
- Provide feedback to team members
- Author lab procedures, protocols, and reports
- Present at internal and external seminars
- Operate, troubleshoot, and maintain instruments
- Collaborate with cross-functional teams
- Support analytical studies and process development
- Ensure close collaboration with local and global functions
Work Experience
- 3 years
Education
- Master's degree
Languages
- English – Business Fluent
Tools & Technologies
- LC-MS
- Orbitrap
- RP-LC
- SEC
- IEX
- CE
Benefits
Mental Health Support
- Well-being support
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Senior Scientist Mass Spectrometry(m/w/x)
Biomolecule characterization using LC-MS for rare disease therapies. 3+ years biopharmaceutical industry experience required. Well-being support, training team members on advanced techniques.
Requirements
- Postgraduate degree (preferably PhD) in biological sciences, biophysics, or analytical chemistry
- 3+ years biopharmaceutical industry experience in biomolecule characterization by LC-MS
- Experience in LC-MS method development, optimization, and qualification using QbD principles
- Advanced expertise in LC-MS bioanalytics for protein/peptide characterization, especially high-resolution MS (e.g., Orbitrap)
- Strong experience with peptide mapping, intact/subunit mass analysis, and MAM
- In-depth knowledge of PTM analysis (glycosylation, deamidation, oxidation, C-terminal variants)
- Expertise in data evaluation, interpretation, and reporting of complex LC-MS datasets
- Experience with additional bioanalytical workflows, particularly LC separation techniques (RP-LC, SEC, IEX, CE) is a strong plus
- Hands-on experience and knowledge in instrument operation and maintenance
- Good understanding of scientific process, including hypothesis development and experimental design (DoE)
- Strong expertise in biomolecule characterization using LC-MS approaches
- Advanced technical knowledge of mass spectrometry techniques and analytical assay development
- Ability to interpret complex analytical datasets and support scientific decision-making
- Strong scientific problem-solving and troubleshooting skills
- Ability to work independently and collaboratively in interdisciplinary and cross-functional teams
- Strong organizational, documentation, and reporting skills
- Scientific enthusiasm, creativity, and hands-on laboratory mindset
- Proficient English verbal and written communication skills
- Ability to provide technical support, guidance, and training to other scientists and team members
Tasks
- Apply technical background in biomolecule characterization using LC-MS
- Develop fit-for-purpose analytical assays
- Direct workflows and provide technical support
- Train team members on advanced techniques
- Contribute to translating innovative platforms into automated methods
- Design and perform MS-based experiments
- Interpret results to support product characterization
- Develop and implement novel analytical methods
- Ensure methods meet quality by design principles
- Qualify methods according to project and product demands
- Act as Subject Matter Expert for mass spectrometry
- Provide scientific leadership and guidance
- Evaluate and implement new technologies
- Manage resources effectively
- Provide feedback to team members
- Author lab procedures, protocols, and reports
- Present at internal and external seminars
- Operate, troubleshoot, and maintain instruments
- Collaborate with cross-functional teams
- Support analytical studies and process development
- Ensure close collaboration with local and global functions
Work Experience
- 3 years
Education
- Master's degree
Languages
- English – Business Fluent
Tools & Technologies
- LC-MS
- Orbitrap
- RP-LC
- SEC
- IEX
- CE
Benefits
Mental Health Support
- Well-being support
Like this job?
BetaYour Career Agent finds similar jobs for you every day.
About the Company
CSL Behring
Industry
Pharmaceuticals
Description
Das Unternehmen ist ein globaler Marktführer in der Biotherapeutik, der innovative Therapien für Patienten mit immunologischen, hämatologischen, kardiovaskulären und anderen Erkrankungen entwickelt.
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