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Senior Principal Statistician, Early Development(m/w/x)
Statistical strategy for early-phase studies, advising senior governance on dose optimization in healthcare R&D. PhD/MSc in Biostatistics/Statistics, 12 years clinical trial experience, and advanced statistical design expertise required. Direct impact on therapeutic area and portfolio decisions.
Requirements
- PhD or MSc in Statistics or Biostatistics
- 12 years experience in clinical trial statistics
- Focus on early development strategy
- Expertise in advanced statistical design
- Interest in AI/ML and real-world data
- Proven leadership in cross-functional projects
- Outstanding communication and influence skills
- Strategic agility and independent decision-making
- Contribution to the broader scientific community
- Cultural respect in a global workspace
Tasks
- Lead statistical strategy for complex early-phase studies
- Advise on therapeutic area and portfolio decisions
- Integrate multimodal data into trial designs
- Represent the function in senior governance discussions
- Drive decisions on dose and regimen optimization
- Co-lead initiatives for statistical operational excellence
- Standardize adaptive design and decision-making frameworks
- Guide statistical content for strategic regulatory engagements
- Author statistical components of submission packages
- Provide technical leadership to cross-functional colleagues
- Evaluate new methods and internal innovation projects
- Align statistical efforts with enterprise AI/ML initiatives
Work Experience
Education
Languages
Tools & Technologies
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Senior Principal Statistician, Early Development(m/w/x)
Statistical strategy for early-phase studies, advising senior governance on dose optimization in healthcare R&D. PhD/MSc in Biostatistics/Statistics, 12 years clinical trial experience, and advanced statistical design expertise required. Direct impact on therapeutic area and portfolio decisions.
Requirements
- PhD or MSc in Statistics or Biostatistics
- 12 years experience in clinical trial statistics
- Focus on early development strategy
- Expertise in advanced statistical design
- Interest in AI/ML and real-world data
- Proven leadership in cross-functional projects
- Outstanding communication and influence skills
- Strategic agility and independent decision-making
- Contribution to the broader scientific community
- Cultural respect in a global workspace
Tasks
- Lead statistical strategy for complex early-phase studies
- Advise on therapeutic area and portfolio decisions
- Integrate multimodal data into trial designs
- Represent the function in senior governance discussions
- Drive decisions on dose and regimen optimization
- Co-lead initiatives for statistical operational excellence
- Standardize adaptive design and decision-making frameworks
- Guide statistical content for strategic regulatory engagements
- Author statistical components of submission packages
- Provide technical leadership to cross-functional colleagues
- Evaluate new methods and internal innovation projects
- Align statistical efforts with enterprise AI/ML initiatives
Work Experience
Education
Languages
Tools & Technologies
About the Company
Roche
Industry
Pharmaceuticals
Description
The company is dedicated to advancing science and ensuring access to healthcare for everyone.
- 1201 F. Hoffmann-La Roche AG
Statistician(m/w/x)
Full-timeOn-siteEntry LevelBasel - 1201 F. Hoffmann-La Roche AG
Computational Statistician - Oncology(m/w/x)
Full-timeOn-siteExperiencedBasel - Novartis
HTA Evidence Synthesis Statistician(m/w/x)
Full-timeOn-siteSeniorBasel - 1201 F. Hoffmann-La Roche AG
Data Scientist in Sensor Data Analytics(m/w/x)
Full-timeOn-siteSeniorBasel - 1201 F. Hoffmann-La Roche AG
Data Strategy & Analytics Lead, Oncology (Hematology)(m/w/x)
Full-timeOn-siteManagementBasel