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RO
Roche
yesterday

Senior Principal Statistician, Early Development(m/w/x)

Basel
Full-timeOn-siteSenior
AI/ML
Data Science

Description

You will drive scientific rigor by leading the statistical design of complex early-phase trials, ensuring data-driven decisions shape the clinical strategy and regulatory success.

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Requirements

  • PhD or MSc in Statistics or Biostatistics
  • 12 years experience in clinical trial statistics
  • Focus on early development strategy
  • Expertise in advanced statistical design
  • Interest in AI/ML and real-world data
  • Proven leadership in cross-functional projects
  • Outstanding communication and influence skills
  • Strategic agility and independent decision-making
  • Contribution to the broader scientific community
  • Cultural respect in a global workspace

Education

Doctoral / PhD
OR
Master's degree

Work Experience

12 years

Tasks

  • Lead statistical strategy for complex early-phase studies
  • Advise on therapeutic area and portfolio decisions
  • Integrate multimodal data into trial designs
  • Represent the function in senior governance discussions
  • Drive decisions on dose and regimen optimization
  • Co-lead initiatives for statistical operational excellence
  • Standardize adaptive design and decision-making frameworks
  • Guide statistical content for strategic regulatory engagements
  • Author statistical components of submission packages
  • Provide technical leadership to cross-functional colleagues
  • Evaluate new methods and internal innovation projects
  • Align statistical efforts with enterprise AI/ML initiatives

Tools & Technologies

Bayesian adaptive trialsAIMLReal-world data applications

Languages

EnglishBusiness Fluent

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