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NONovartis Pharma AG

Senior Expert Science & Technology - PRD Chemist(m/w/x)

Basel
Full-timeOn-siteSenior

Developing manufacturing and analytical processes for Antibody-Oligonucleotide conjugates. PhD and PostDoc in organic chemistry with bio-conjugation specialization required. Lab-based work in bioconjugation chemistry, coordinating pilot plant transfers.

Requirements

  • PhD and PostDoc in organic chemistry
  • Specialization in bio-conjugation or chemical modification of fermentation products
  • Knowledge in chemical bioconjugation or modification of fermentation products
  • Experience with Antibody-Drug Conjugations or complex molecular structures
  • 2-5 years experience in synthesis/chemical process development
  • Piloting experience under GMP is a benefit
  • Independent and self-motivated workstyle
  • Team orientation
  • Adequate communication style
  • Advanced knowledge of Office package
  • Advanced knowledge of DoE tools
  • Adequate knowledge of English language (oral and written)
  • German language skills are beneficial
  • Other language skills are beneficial

Tasks

  • Lead development of chemistry and manufacturing pathways for AOCs
  • Contribute to Novartis BD&L activities in bioconjugation chemistry
  • Design and execute experiments in the lab
  • Interpret and report experimental data and results
  • Coordinate timely transfer of manufacturing instructions to pilot plant
  • Collaborate with internal and external partners on drug development
  • Ensure quality and timely delivery of new nucleotide drugs
  • Prepare process documentation for regulatory filings
  • Participate in scientific exchange groups within Novartis and academia
  • Maintain strong relationships with customers

Work Experience

  • 2 - 5 years

Education

  • Doctoral / PhD

Languages

  • EnglishBusiness Fluent
  • GermanBasic

Tools & Technologies

  • Office package
  • DoE tools
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