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Scientist R&D Molecular Design(m/w/x)
Designing and screening phage display libraries with NGS workflows for therapeutic discovery at a human protein manufacturer. Ph.D. in Molecular Biology or M.Sc. with 3+ years relevant experience, plus hands-on phage display platforms experience required. 30 days vacation, company restaurant with subsidies, free drinks.
Requirements
- Ph.D. in Molecular Biology, Biochemistry, Immunology, or related field or M.Sc. with at least 3 years relevant professional experience
- Hands-on experience with phage display platforms and antibody/peptide selection techniques
- Strong knowledge of library design and construction, molecular cloning, and expression systems
- Proficiency in NGS workflows for diversity analysis and hit tracking
- Excellent scientific research, data analysis, and interpretation skills
- Excellent communication skills in English; German knowledge is a plus
- Strong problem-solving ability, attention to detail, and capacity to work independently and collaboratively
- Understanding of antibody structure-function relationships and engineering strategies
- Experience with automation and high-throughput screening
- Programming or scripting experience for data analysis
- Familiarity with other display technologies
Tasks
- Design and construct phage display libraries for therapeutic discovery campaigns
- Perform selection and screening of phage libraries using biopanning and enrichment strategies
- Integrate Next-Generation Sequencing (NGS) workflows for library quality control and diversity assessment
- Analyze sequencing and experimental data to monitor enrichment and guide candidate optimization
- Develop and optimize directed evolution strategies to improve affinity, stability, and developability
- Collaborate with protein engineering, computational biology, and project teams
- Coordinate external lead discovery activities
- Prepare scientific reports and documentation
- Present findings in project and departmental meetings
- Stay informed about the latest scientific developments and apply insights to ongoing projects
Work Experience
- 3 years
Education
- Master's degree
Languages
- English – Business Fluent
- German – Basic
Tools & Technologies
- NGS workflows
- bioinformatics tools
Benefits
Flexible Working
- Flexible working hours
Learning & Development
- Regular opportunities for further training
More Vacation Days
- 30 days vacation
Free or Subsidized Food
- Own company restaurant with subsidies
Snacks & Drinks
- Free drinks
Not a perfect match?
- AbbVieFull-time/Part-timeOn-siteExperiencedLudwigshafen am Rhein
- Octapharma Biopharmaceuticals GmbH
Expert R&D Automation and Data Management(m/w/x)
Full-timeOn-siteSeniorHeidelberg - AbbVie
Scientist I – Bioassay Sciences and Development(m/w/x)
Full-time/Part-timeOn-siteExperiencedLudwigshafen am Rhein - Octapharma Biopharmaceuticals GmbH
Project Manager R&D(m/w/x)
Full-timeOn-siteExperiencedHeidelberg - AbbVie
Principal Research Scientist I/II / Biologics Drug Product Lead (R&D)(m/w/x)
Full-timeOn-siteSeniorLudwigshafen am Rhein
Scientist R&D Molecular Design(m/w/x)
Designing and screening phage display libraries with NGS workflows for therapeutic discovery at a human protein manufacturer. Ph.D. in Molecular Biology or M.Sc. with 3+ years relevant experience, plus hands-on phage display platforms experience required. 30 days vacation, company restaurant with subsidies, free drinks.
Requirements
- Ph.D. in Molecular Biology, Biochemistry, Immunology, or related field or M.Sc. with at least 3 years relevant professional experience
- Hands-on experience with phage display platforms and antibody/peptide selection techniques
- Strong knowledge of library design and construction, molecular cloning, and expression systems
- Proficiency in NGS workflows for diversity analysis and hit tracking
- Excellent scientific research, data analysis, and interpretation skills
- Excellent communication skills in English; German knowledge is a plus
- Strong problem-solving ability, attention to detail, and capacity to work independently and collaboratively
- Understanding of antibody structure-function relationships and engineering strategies
- Experience with automation and high-throughput screening
- Programming or scripting experience for data analysis
- Familiarity with other display technologies
Tasks
- Design and construct phage display libraries for therapeutic discovery campaigns
- Perform selection and screening of phage libraries using biopanning and enrichment strategies
- Integrate Next-Generation Sequencing (NGS) workflows for library quality control and diversity assessment
- Analyze sequencing and experimental data to monitor enrichment and guide candidate optimization
- Develop and optimize directed evolution strategies to improve affinity, stability, and developability
- Collaborate with protein engineering, computational biology, and project teams
- Coordinate external lead discovery activities
- Prepare scientific reports and documentation
- Present findings in project and departmental meetings
- Stay informed about the latest scientific developments and apply insights to ongoing projects
Work Experience
- 3 years
Education
- Master's degree
Languages
- English – Business Fluent
- German – Basic
Tools & Technologies
- NGS workflows
- bioinformatics tools
Benefits
Flexible Working
- Flexible working hours
Learning & Development
- Regular opportunities for further training
More Vacation Days
- 30 days vacation
Free or Subsidized Food
- Own company restaurant with subsidies
Snacks & Drinks
- Free drinks
About the Company
Octapharma Biopharmaceuticals GmbH
Industry
Pharmaceuticals
Description
The company is one of the largest human protein manufacturers in the world, developing and producing medicines sourced from human plasma and human cell lines.
Not a perfect match?
- AbbVie
Scientist I – Bioassay Sciences and Development(m/w/x)
Full-time/Part-timeOn-siteExperiencedLudwigshafen am Rhein - Octapharma Biopharmaceuticals GmbH
Expert R&D Automation and Data Management(m/w/x)
Full-timeOn-siteSeniorHeidelberg - AbbVie
Scientist I – Bioassay Sciences and Development(m/w/x)
Full-time/Part-timeOn-siteExperiencedLudwigshafen am Rhein - Octapharma Biopharmaceuticals GmbH
Project Manager R&D(m/w/x)
Full-timeOn-siteExperiencedHeidelberg - AbbVie
Principal Research Scientist I/II / Biologics Drug Product Lead (R&D)(m/w/x)
Full-timeOn-siteSeniorLudwigshafen am Rhein