Novartis Pharma AG
Principal Scientist - Translational Intestinal Immunology(m/w/x)
Full-timeOn-siteExperienced
Basel
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NONovartis Pharma AG
Principal Scientist - Translational Intestinal Immunology(m/w/x)
Basel
Full-timeOn-siteExperienced
Nejo AI Summary
Linking human IBD biology to druggable targets using in vitro human models and biosamples. At least 3 years translational research expertise required. Work in a 15-person R&D team focused on next-gen medicines.
Requirements
- PhD or MD in Mucosal Immunology, Gastroenterology, Barrier Immunology, or related field
- At least 3 years translational research expertise in interdisciplinary setting
- Mastery of immunological/cell biology/molecular biology assays
- Mastery of in vitro human models relevant to IBD and mucosal immunity
- Ability to conduct experiments using in vitro human systems and biosamples
- Experience with sample-tracking best practices and consent/ethics
- Collaboration with data scientists
- Ensuring high quality experimental design and reproducibility
- Track record of completing projects on schedule
- Mentoring junior researchers
- Contributing to drug discovery programs
- Experience in translational academic/clinical setting
- Data Science literacy
- Confidence interpreting multi-omic outputs and statistical analyses
- Gastroenterology knowledge
- Gastrointestinal Disease knowledge
- Inflammatory Bowel Diseases knowledge
Tasks
- Design and execute mechanistic experiments
- Link human disease biology to druggable targets
- Accelerate preclinical compound development
- Strengthen understanding of drug modes of action
- Differentiate novel drugs from standard-of-care treatments
- Leverage human biosamples for decision-making data
- Position candidate molecules for clinical trials
- Conduct target validation studies
- Perform MoA studies
- Develop biomarker strategies
- Partner with early clinical teams
- Test clinical hypotheses for early clinical strategies
- Champion data-driven target discovery
- Collaborate with data scientists and in vivo biology labs
- Connect quantitative methods to patient heterogeneity
- Drive a culture of collaboration
- Foster talent development
- Maintain integrity in research
Work Experience
- 3 years
Education
- Doctoral / PhD
Languages
- English – Business Fluent
Tools & Technologies
- multi-parametric flow cytometry
- IBD
- mucosal immunity
- PBMCs
- primary immune cells
- epithelial cells
- tissue explants
- Data Science
- multi-omic outputs
- statistical analyses
- Gastroenterology
- Gastrointestinal Disease
- Inflammatory Bowel Diseases
Find the original job posting in its most current version here. Nejo automatically captured this job from the website of Novartis Pharma AG and processed the information on Nejo with the help of AI for you. Despite careful analysis, some information may be incomplete or inaccurate. Please always verify all details in the original posting! Content and copyrights of the original posting belong to the advertising company.
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NONovartis Pharma AG
Principal Scientist - Translational Intestinal Immunology(m/w/x)
Basel
Full-timeOn-siteExperienced
Nejo AI Summary
Linking human IBD biology to druggable targets using in vitro human models and biosamples. At least 3 years translational research expertise required. Work in a 15-person R&D team focused on next-gen medicines.
Requirements
- PhD or MD in Mucosal Immunology, Gastroenterology, Barrier Immunology, or related field
- At least 3 years translational research expertise in interdisciplinary setting
- Mastery of immunological/cell biology/molecular biology assays
- Mastery of in vitro human models relevant to IBD and mucosal immunity
- Ability to conduct experiments using in vitro human systems and biosamples
- Experience with sample-tracking best practices and consent/ethics
- Collaboration with data scientists
- Ensuring high quality experimental design and reproducibility
- Track record of completing projects on schedule
- Mentoring junior researchers
- Contributing to drug discovery programs
- Experience in translational academic/clinical setting
- Data Science literacy
- Confidence interpreting multi-omic outputs and statistical analyses
- Gastroenterology knowledge
- Gastrointestinal Disease knowledge
- Inflammatory Bowel Diseases knowledge
Tasks
- Design and execute mechanistic experiments
- Link human disease biology to druggable targets
- Accelerate preclinical compound development
- Strengthen understanding of drug modes of action
- Differentiate novel drugs from standard-of-care treatments
- Leverage human biosamples for decision-making data
- Position candidate molecules for clinical trials
- Conduct target validation studies
- Perform MoA studies
- Develop biomarker strategies
- Partner with early clinical teams
- Test clinical hypotheses for early clinical strategies
- Champion data-driven target discovery
- Collaborate with data scientists and in vivo biology labs
- Connect quantitative methods to patient heterogeneity
- Drive a culture of collaboration
- Foster talent development
- Maintain integrity in research
Work Experience
- 3 years
Education
- Doctoral / PhD
Languages
- English – Business Fluent
Tools & Technologies
- multi-parametric flow cytometry
- IBD
- mucosal immunity
- PBMCs
- primary immune cells
- epithelial cells
- tissue explants
- Data Science
- multi-omic outputs
- statistical analyses
- Gastroenterology
- Gastrointestinal Disease
- Inflammatory Bowel Diseases
Find the original job posting in its most current version here. Nejo automatically captured this job from the website of Novartis Pharma AG and processed the information on Nejo with the help of AI for you. Despite careful analysis, some information may be incomplete or inaccurate. Please always verify all details in the original posting! Content and copyrights of the original posting belong to the advertising company.
About the Company
Novartis Pharma AG
Industry
Pharmaceuticals
Description
Das Unternehmen setzt sich für Vielfalt, Chancengleichheit und Inklusion ein und fördert innovative Lösungen zur Verbesserung der Patientenversorgung.
Not a perfect match?
- Novartis Pharma AG
Principal Scientist - Translational Intestinal Immunology(m/w/x)
Full-timeOn-siteExperiencedBasel - Roche
Senior Scientist - Mucosal Immunology(m/w/x)
Full-timeOn-siteManagementBasel - Institute of Human Biology (IHB)
Post Doctorate Scientist in Intestinal Inflammation(m/w/x)
Full-timeOn-siteSeniorBasel - 1201 F. Hoffmann-La Roche AG
Clinical Scientist immunology(m/w/x)
Full-timeOn-siteSeniorBasel - Roche
Medical Director, Gastroenterology, Early Clinical Development(m/w/x)
Full-timeOn-siteSeniorBasel