Roche
Post Doctorate Scientist (IHB) - In Vitro Modeling Adaptive Immunologist(m/w/x)
Full-timeOn-siteExperienced
Basel
New Job?Nejo!
Your personal AI career agent
F.F. Hoffmann-La Roche AG
Post Doctoral Scientist (IHB) - Computational Immunology(m/w/x)
Basel
Full-timeOn-siteExperienced
Data Science
Nejo AI Summary
Computational research on immune cell states in human neuroinflammation, integrating multi-omic datasets. Ph.D. in related field, completed within last four years, required. Early-career focus, R/Python programming, single-cell/spatial data experience.
Requirements
- Ph.D. in Immunology, Computational Biology, Bioinformatics, Systems Biology, or related field
- Early-career researcher, Ph.D. completed within last four years
- Strong programming skills in R and Python
- Experience with multi-omic datasets, ideally single-cell and/or spatial
- Expertise in T- and B-cell biology analysis
- Knowledge of immune cell subsets and heterogeneity
- Experience with immune repertoire profiling (AIRR-seq, Rep-seq, scRNA-seq + VDJ)
- Experience with shared computing clusters / HPC environments
- Strong interest in human immunology and neuroinflammation
- Ability to work effectively across scientific functions
- Ability to build strong, productive collaborations
- Strong communication skills
- Professional fluency in spoken and written English
- Proactive, “go-getter” mindset
- Ability to manage priorities
- Ability to adapt as research evolves
- Contribute to a team-oriented culture
- Research experience in adaptive neuroinflammation
- Knowledge of meningeal biology
- Knowledge of tissue-specific immune niches
- Experience analyzing spatial transcriptomics, proteomics, or related spatial omics
- Familiarity with stromal biology
- Experience with human translational and multi-omic datasets
- Experience as an experimental scientist
- Experience in close partnership with wet-lab teams
- Strong understanding of experimental design
- Strong understanding of technical execution of assays
- Strong understanding of assay limitations
- Interest in translating human biology insights into therapeutic strategies
Tasks
- Lead computational research on immune cell states in human neuroinflammation
- Integrate multi-omic datasets to uncover disease mechanisms and therapeutic targets
- Contribute to developing a comprehensive human atlas of neuroinflammation
- Identify cellular states and molecular signatures in healthy and diseased donors
- Apply computational and biological insights to high-dimensional datasets
- Generate hypotheses and guide future translational research
- Analyze T- and B-cell repertoires using high-throughput methods
- Conduct AIRR-seq, Rep-seq, and scRNA-seq + VDJ dataset analyses
- Collaborate with IHB and pRED scientists across various fields
- Translate human biology findings into portfolio-relevant questions and strategies
- Contribute to scientific manuscripts, internal presentations, and conference talks
- Communicate computational and biological findings to diverse audiences
- Support a collaborative and inclusive research culture
Work Experience
- approx. 1 - 4 years
Education
- Doctoral / PhD
Languages
- English – Business Fluent
Tools & Technologies
- R
- Python
- AIRR-seq
- Rep-seq
- scRNA-seq
- VDJ
Find the original job posting in its most current version here. Nejo automatically captured this job from the website of F. Hoffmann-La Roche AG and processed the information on Nejo with the help of AI for you. Despite careful analysis, some information may be incomplete or inaccurate. Please always verify all details in the original posting! Content and copyrights of the original posting belong to the advertising company.
Not a perfect match?
- F. Hoffmann-La Roche AG
Post Doctorate Scientist - Single Cell Technologies(m/w/x)
Full-timeOn-siteSeniorBasel - Roche
Sr. Scientist - Computational Biology(m/w/x)
Full-timeOn-siteExperiencedBasel - 1201 F. Hoffmann-La Roche AG
Post Doctorate Scientist Single Cell Technologies(m/w/x)
Full-timeOn-siteExperiencedBasel - F. Hoffmann-La Roche AG
PhD Student in Single Cell Technologies(m/w/x)
Full-timeOn-siteSeniorBasel
F.F. Hoffmann-La Roche AG
Post Doctoral Scientist (IHB) - Computational Immunology(m/w/x)
Basel
Full-timeOn-siteExperienced
Data Science
Nejo AI Summary
Computational research on immune cell states in human neuroinflammation, integrating multi-omic datasets. Ph.D. in related field, completed within last four years, required. Early-career focus, R/Python programming, single-cell/spatial data experience.
Requirements
- Ph.D. in Immunology, Computational Biology, Bioinformatics, Systems Biology, or related field
- Early-career researcher, Ph.D. completed within last four years
- Strong programming skills in R and Python
- Experience with multi-omic datasets, ideally single-cell and/or spatial
- Expertise in T- and B-cell biology analysis
- Knowledge of immune cell subsets and heterogeneity
- Experience with immune repertoire profiling (AIRR-seq, Rep-seq, scRNA-seq + VDJ)
- Experience with shared computing clusters / HPC environments
- Strong interest in human immunology and neuroinflammation
- Ability to work effectively across scientific functions
- Ability to build strong, productive collaborations
- Strong communication skills
- Professional fluency in spoken and written English
- Proactive, “go-getter” mindset
- Ability to manage priorities
- Ability to adapt as research evolves
- Contribute to a team-oriented culture
- Research experience in adaptive neuroinflammation
- Knowledge of meningeal biology
- Knowledge of tissue-specific immune niches
- Experience analyzing spatial transcriptomics, proteomics, or related spatial omics
- Familiarity with stromal biology
- Experience with human translational and multi-omic datasets
- Experience as an experimental scientist
- Experience in close partnership with wet-lab teams
- Strong understanding of experimental design
- Strong understanding of technical execution of assays
- Strong understanding of assay limitations
- Interest in translating human biology insights into therapeutic strategies
Tasks
- Lead computational research on immune cell states in human neuroinflammation
- Integrate multi-omic datasets to uncover disease mechanisms and therapeutic targets
- Contribute to developing a comprehensive human atlas of neuroinflammation
- Identify cellular states and molecular signatures in healthy and diseased donors
- Apply computational and biological insights to high-dimensional datasets
- Generate hypotheses and guide future translational research
- Analyze T- and B-cell repertoires using high-throughput methods
- Conduct AIRR-seq, Rep-seq, and scRNA-seq + VDJ dataset analyses
- Collaborate with IHB and pRED scientists across various fields
- Translate human biology findings into portfolio-relevant questions and strategies
- Contribute to scientific manuscripts, internal presentations, and conference talks
- Communicate computational and biological findings to diverse audiences
- Support a collaborative and inclusive research culture
Work Experience
- approx. 1 - 4 years
Education
- Doctoral / PhD
Languages
- English – Business Fluent
Tools & Technologies
- R
- Python
- AIRR-seq
- Rep-seq
- scRNA-seq
- VDJ
Find the original job posting in its most current version here. Nejo automatically captured this job from the website of F. Hoffmann-La Roche AG and processed the information on Nejo with the help of AI for you. Despite careful analysis, some information may be incomplete or inaccurate. Please always verify all details in the original posting! Content and copyrights of the original posting belong to the advertising company.
About the Company
F. Hoffmann-La Roche AG
Industry
Pharmaceuticals
Description
Das Unternehmen ist ein führender Anbieter von pharmazeutischen Wirkstoffen und setzt sich für die Gesundheitsversorgung weltweit ein.
Not a perfect match?
- Roche
Post Doctorate Scientist (IHB) - In Vitro Modeling Adaptive Immunologist(m/w/x)
Full-timeOn-siteExperiencedBasel - F. Hoffmann-La Roche AG
Post Doctorate Scientist - Single Cell Technologies(m/w/x)
Full-timeOn-siteSeniorBasel - Roche
Sr. Scientist - Computational Biology(m/w/x)
Full-timeOn-siteExperiencedBasel - 1201 F. Hoffmann-La Roche AG
Post Doctorate Scientist Single Cell Technologies(m/w/x)
Full-timeOn-siteExperiencedBasel - F. Hoffmann-La Roche AG
PhD Student in Single Cell Technologies(m/w/x)
Full-timeOn-siteSeniorBasel