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SUSUSONITY

Internship: Optimization of Cell Line Development(m/w/x)

Corsier-sur-Vevey
Full-timeInternshipOn-site

Investigating protein expression systems and uncoupling mAb molecule expression from CHO cell pathways. Master/Engineer student in biology or related field required. Access to development opportunities, culture of inclusion.

Requirements

  • Interest in molecular/cellular biology and biotechnologies
  • Excellent communication skills
  • Excellent organizational skills
  • Passion for learning
  • Master/Engineer student in biology, molecular or cellular biology, biotechnology or related subject
  • Experience in sterile culture handling
  • Programming in R or Python
  • French and/or English language skills
  • Ongoing study

Tasks

  • Investigate implementing protein expression systems
  • Uncouple mAb molecule expression from CHO cell pathways
  • Lead generation of cell lines expressing exogenous RNA polymerase
  • Evaluate impact on mAb yield
  • Generate and characterize modified cell pools
  • Perform productivity assays to measure mAb titer
  • Perform single cell cloning of best pools
  • Obtain clonal cell lines
  • Screen clonal cell lines for enzyme expression using ddPCR
  • Compare enzyme-expressing and control cell lines at different scales
  • Assess productivity using Beacon technology
  • Utilize automated robotic platforms
  • Operate Ambr15 system
  • Analyze experimental data using chosen programming language
  • Design experiments with experienced researchers
  • Execute experiments with experienced researchers
  • Analyze experimental data
  • Present findings to the wider team

Education

  • Currently in higher education

Languages

  • FrenchBusiness Fluent
  • EnglishBusiness Fluent

Tools & Technologies

  • R
  • Python

Benefits

Career Advancement

  • Access to opportunities for development and growth

Informal Culture

  • Culture of inclusion and belonging

Purpose-Driven Work

  • Empowerment to work magic
  • Human progress championing
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