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RORoche

Intern (Machine Learning – RNA Splicing)(m/w/x)

Basel
Full-timeInternshipOn-site
AI/ML
Data Science

Developing reproducible pipelines for sequence scoring and integrating state-of-the-art splicing prediction models at a global healthcare research organization. Master's degree in Computational Biology or related field, plus strong Python skills essential. Direct contribution to therapeutic sequence design with cutting-edge predictive models.

Requirements

  • Master's degree (past 12 months) or current Master's/PhD enrollment in Computational Biology, Bioinformatics, Machine Learning, Computer Science, or related field
  • Strong Python programming skills
  • Experience with ML frameworks (PyTorch or TensorFlow)
  • Familiarity with RNA and DNA biology
  • Experience with reproducible research workflows (Git, HPC/cloud)
  • Strong communication skills
  • English proficiency (written and spoken)
  • Experience with deep learning for biological sequences
  • Knowledge of RNA splicing biology
  • Familiarity with AAV gene therapy or RNA therapeutics
  • Track record of scientific software development
  • Experience operationalizing ML models
  • Experience building lightweight user-facing tools
  • Non EU/EFTA student university enrollment for internship duration
  • Internship as mandatory curriculum part for Non EU/EFTA students

Tasks

  • Integrate and benchmark state-of-the-art splicing prediction models
  • Develop reproducible pipelines for sequence scoring
  • Support model-guided design of therapeutic sequence constructs
  • Support prioritization of therapeutic sequence constructs
  • Contribute to structured benchmarking against experimental data
  • Contribute to documentation for researcher adoption
  • Contribute to usability for researcher adoption

Education

  • Currently in higher education

Languages

  • EnglishBusiness Fluent

Tools & Technologies

  • Python
  • PyTorch
  • TensorFlow
  • Git
  • HPC
  • Cloud environments
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