Sanofi-Aventis Deutschland GmbH
Translational T1/17 Immunology Lead(m/w/x)
Vollzeitnur vor OrtSenior
Frankfurt am Main
Neuer Job?Nejo!
Dein persönlicher KI-Karriere-Agent
SASanofi-Aventis Deutschland GmbH
Senior Scientist - Transgenic Technology and Model Characterization(m/w/x)
Frankfurt am Main
VollzeitVor OrtSenior
Nejo KI-Zusammenfassung
Designing and validating genetically modified rodent models for biopharma R&D. Advanced multicolor spectral flow cytometry and unsupervised analysis expertise required. 14 weeks' gender-neutral parental leave.
Anforderungen
- PhD in immunology, molecular biology, mouse genetics, or related biological sciences
- Minimum 5 years hands-on experience in multicolor spectral flow cytometry (minimum 15 colors), including panel design, optimization, analysis, and critical interpretation
- Extensive experience with spectral cytometers (Cytek, BD, Sony, or similar platforms)
- Proven expertise in unsupervised flow cytometry analysis (OMIQ, FlowJo, or equivalent) - mandatory
- Demonstrated proficiency in statistical analysis using Prism - mandatory
- Strong background in mouse molecular genetics and immuno-phenotyping
- Experience in project management: designing, organizing, and executing experiments aligned with project objectives
- Expert-level knowledge in immunology and biological sciences
- Proficiency in culturing murine primary cells and performing cell isolation techniques
- Competency in mice experimentation (Designer level) including genotyping, breeding, and various injection routes
- Strong computer skills including Microsoft Office Suite (Word, PowerPoint, Excel) and database management systems
- English: Full professional proficiency required
- Excellent organizational and communication skills
- Ability to lead and work collaboratively within multidisciplinary teams
- Strong motivation to contribute to developing genetically modified preclinical animal models
- Proactive approach to implementing innovative procedures and methodologies
- Demonstrated ability to manage multiple projects and meet deadlines
- Detail-oriented with commitment to data quality and integrity
- Self-motivated with ability to work independently and as part of a team
- Strong problem-solving skills and scientific curiosity
- Commitment to continuous learning and professional development
Aufgaben
- Conduct molecular and immuno-phenotypic characterization of genetically modified rodent models
- Design, organize, and execute validation experiments for new transgenic models
- Collaborate with investigators and researchers to define project needs
- Perform advanced multicolor spectral flow cytometry, including panel design and optimization
- Interpret critical flow cytometry data
- Conduct unsupervised flow cytometry analysis using OMIQ and FlowJo
- Characterize diverse immune and non-immune cell sub-populations by cytometry
- Culture murine primary cells, including isolation, culture, activation, and differentiation
- Prepare comprehensive reports and presentations for stakeholders
- Ensure data quality and integrity through compilation and database entry
- Manage electronic laboratory notebooks and maintain documentation standards
- Apply statistical analysis methods using Prism and other software
- Maintain working relationships with model providers, CROs, and colleagues
- Provide expert guidance on transgenic research models
- Recommend optimal validation strategies
- Share knowledge through oral presentations and discussions
- Implement and recommend new procedures for model development
- Conduct mice experimentation: genotyping, breeding, injections, immunization, and sample processing
- Follow HSE requirements for laboratory activities
- Contribute to laboratory management and best practice development
Berufserfahrung
- 5 Jahre
Ausbildung
- Doktor / Ph.D.
Sprachen
- Englisch – verhandlungssicher
Tools & Technologien
- Cytek
- BD
- Sony
- OMIQ
- FlowJo
- Prism
- Microsoft Office Suite
- Word
- PowerPoint
- Excel
Benefits
Gesundheits- & Fitnessangebote
- High-quality healthcare
- Prevention and wellness programs
Großzügige Elternzeit
- 14 weeks' gender-neutral parental leave
Die Originalanzeige dieses Stellenangebotes in der aktuellsten Version findest du hier. Nejo hat diesen Job automatisch von der Website des Unternehmens Sanofi-Aventis Deutschland GmbH erfasst und die Informationen auf Nejo mit Hilfe von KI für dich aufbereitet. Trotz sorgfältiger Analyse können einzelne Informationen unvollständig oder ungenau sein. Bitte prüfe immer alle Angaben in der Originalanzeige! Inhalte und Urheberrechte der Originalanzeige liegen beim ausschreibenden Unternehmen.
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Scientist - Tech Area(m/w/x)
Vollzeitnur vor OrtSeniorFrankfurt am Main - Sanofi
Laborleiter:in IDD - In vitro Biologie(m/w/x)
VollzeitBefristeter Vertragnur vor OrtSeniorFrankfurt am Main - Sanofi-Aventis Deutschland GmbH
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Vollzeitnur vor OrtBerufserfahrenFrankfurt am Main
SASanofi-Aventis Deutschland GmbH
Senior Scientist - Transgenic Technology and Model Characterization(m/w/x)
Frankfurt am Main
VollzeitVor OrtSenior
Nejo KI-Zusammenfassung
Designing and validating genetically modified rodent models for biopharma R&D. Advanced multicolor spectral flow cytometry and unsupervised analysis expertise required. 14 weeks' gender-neutral parental leave.
Anforderungen
- PhD in immunology, molecular biology, mouse genetics, or related biological sciences
- Minimum 5 years hands-on experience in multicolor spectral flow cytometry (minimum 15 colors), including panel design, optimization, analysis, and critical interpretation
- Extensive experience with spectral cytometers (Cytek, BD, Sony, or similar platforms)
- Proven expertise in unsupervised flow cytometry analysis (OMIQ, FlowJo, or equivalent) - mandatory
- Demonstrated proficiency in statistical analysis using Prism - mandatory
- Strong background in mouse molecular genetics and immuno-phenotyping
- Experience in project management: designing, organizing, and executing experiments aligned with project objectives
- Expert-level knowledge in immunology and biological sciences
- Proficiency in culturing murine primary cells and performing cell isolation techniques
- Competency in mice experimentation (Designer level) including genotyping, breeding, and various injection routes
- Strong computer skills including Microsoft Office Suite (Word, PowerPoint, Excel) and database management systems
- English: Full professional proficiency required
- Excellent organizational and communication skills
- Ability to lead and work collaboratively within multidisciplinary teams
- Strong motivation to contribute to developing genetically modified preclinical animal models
- Proactive approach to implementing innovative procedures and methodologies
- Demonstrated ability to manage multiple projects and meet deadlines
- Detail-oriented with commitment to data quality and integrity
- Self-motivated with ability to work independently and as part of a team
- Strong problem-solving skills and scientific curiosity
- Commitment to continuous learning and professional development
Aufgaben
- Conduct molecular and immuno-phenotypic characterization of genetically modified rodent models
- Design, organize, and execute validation experiments for new transgenic models
- Collaborate with investigators and researchers to define project needs
- Perform advanced multicolor spectral flow cytometry, including panel design and optimization
- Interpret critical flow cytometry data
- Conduct unsupervised flow cytometry analysis using OMIQ and FlowJo
- Characterize diverse immune and non-immune cell sub-populations by cytometry
- Culture murine primary cells, including isolation, culture, activation, and differentiation
- Prepare comprehensive reports and presentations for stakeholders
- Ensure data quality and integrity through compilation and database entry
- Manage electronic laboratory notebooks and maintain documentation standards
- Apply statistical analysis methods using Prism and other software
- Maintain working relationships with model providers, CROs, and colleagues
- Provide expert guidance on transgenic research models
- Recommend optimal validation strategies
- Share knowledge through oral presentations and discussions
- Implement and recommend new procedures for model development
- Conduct mice experimentation: genotyping, breeding, injections, immunization, and sample processing
- Follow HSE requirements for laboratory activities
- Contribute to laboratory management and best practice development
Berufserfahrung
- 5 Jahre
Ausbildung
- Doktor / Ph.D.
Sprachen
- Englisch – verhandlungssicher
Tools & Technologien
- Cytek
- BD
- Sony
- OMIQ
- FlowJo
- Prism
- Microsoft Office Suite
- Word
- PowerPoint
- Excel
Benefits
Gesundheits- & Fitnessangebote
- High-quality healthcare
- Prevention and wellness programs
Großzügige Elternzeit
- 14 weeks' gender-neutral parental leave
Die Originalanzeige dieses Stellenangebotes in der aktuellsten Version findest du hier. Nejo hat diesen Job automatisch von der Website des Unternehmens Sanofi-Aventis Deutschland GmbH erfasst und die Informationen auf Nejo mit Hilfe von KI für dich aufbereitet. Trotz sorgfältiger Analyse können einzelne Informationen unvollständig oder ungenau sein. Bitte prüfe immer alle Angaben in der Originalanzeige! Inhalte und Urheberrechte der Originalanzeige liegen beim ausschreibenden Unternehmen.
Über das Unternehmen
Sanofi-Aventis Deutschland GmbH
Branche
Pharmaceuticals
Beschreibung
Das Unternehmen bietet Arzneimittel zur Prävention von Herz-Kreislauf-Erkrankungen an und setzt sich für die Verbesserung der Lebensqualität ein.
Noch nicht perfekt?
- Sanofi-Aventis Deutschland GmbH
Translational T1/17 Immunology Lead(m/w/x)
Vollzeitnur vor OrtSeniorFrankfurt am Main - Sanofi
Scientist high-throughput Biophysical Characterization(m/w/x)
Vollzeitnur vor OrtBerufserfahrenFrankfurt am Main - Sanofi-Aventis Deutschland GmbH
Scientist - Tech Area(m/w/x)
Vollzeitnur vor OrtSeniorFrankfurt am Main - Sanofi
Laborleiter:in IDD - In vitro Biologie(m/w/x)
VollzeitBefristeter Vertragnur vor OrtSeniorFrankfurt am Main - Sanofi-Aventis Deutschland GmbH
Scientist Protein Analytics(m/w/x)
Vollzeitnur vor OrtBerufserfahrenFrankfurt am Main