Principal Scientist - Mid/Large Scale Oligonucleotide Synthesis, xRNA Therapeutics(m/w/x)

Beschreibung

In this leadership role, you will drive the scale-up of innovative siRNA therapies by managing a specialized synthesis facility and mentoring a team of scientists to advance the drug pipeline.

Anforderungen

• •Ph.D. in Chemistry, oligonucleotide synthesis focus
• •2–3 years of industry experience
• •Oligonucleotide solid‑phase synthesis and downstream processing
• •Expertise in process development
• •Leadership capabilities and scientific team development
• •Innovation implementation in global team environments
• •Independent problem-solving skills
• •Highly collaborative mindset
• •Effective multi-priority management and objective focus
• •Excellent verbal and written communication skills

Aufgaben

• •Plan and execute large-scale solid-phase synthesis
• •Purify and analyze chemically modified oligonucleotides
• •Oversee a state-of-the-art synthesis facility
• •Manage capital and consumables budgets efficiently
• •Lead and mentor a specialized team of scientists
• •Support the growing siRNA portfolio at millimole scale
• •Deliver high-quality materials for screening and studies
• •Collaborate with discovery teams in Basel and Cambridge
• •Optimize methodologies for enhanced synthesis efficiency
• •Partner with chemists to scale up new siRNA chemistries
• •Document findings for patent applications and publications
• •Train team members by sharing technical expertise
• •Apply strong problem-solving skills to scientific challenges

Tools & Technologien

Benefits