Dein persönlicher KI-Karriere-Agent
Principal Scientist - Translational Intestinal Immunology(m/w/x)
Linking human IBD biology to druggable targets using in vitro human models and biosamples. At least 3 years translational research expertise required. Work in a 15-person R&D team focused on next-gen medicines.
Anforderungen
- PhD or MD in Mucosal Immunology, Gastroenterology, Barrier Immunology, or related field
- At least 3 years translational research expertise in interdisciplinary setting
- Mastery of immunological/cell biology/molecular biology assays
- Mastery of in vitro human models relevant to IBD and mucosal immunity
- Ability to conduct experiments using in vitro human systems and biosamples
- Experience with sample-tracking best practices and consent/ethics
- Collaboration with data scientists
- Ensuring high quality experimental design and reproducibility
- Track record of completing projects on schedule
- Mentoring junior researchers
- Contributing to drug discovery programs
- Experience in translational academic/clinical setting
- Data Science literacy
- Confidence interpreting multi-omic outputs and statistical analyses
- Gastroenterology knowledge
- Gastrointestinal Disease knowledge
- Inflammatory Bowel Diseases knowledge
Aufgaben
- Design and execute mechanistic experiments
- Link human disease biology to druggable targets
- Accelerate preclinical compound development
- Strengthen understanding of drug modes of action
- Differentiate novel drugs from standard-of-care treatments
- Leverage human biosamples for decision-making data
- Position candidate molecules for clinical trials
- Conduct target validation studies
- Perform MoA studies
- Develop biomarker strategies
- Partner with early clinical teams
- Test clinical hypotheses for early clinical strategies
- Champion data-driven target discovery
- Collaborate with data scientists and in vivo biology labs
- Connect quantitative methods to patient heterogeneity
- Drive a culture of collaboration
- Foster talent development
- Maintain integrity in research
Berufserfahrung
- 3 Jahre
Ausbildung
- Doktor / Ph.D.
Sprachen
- Englisch – verhandlungssicher
Tools & Technologien
- multi-parametric flow cytometry
- IBD
- mucosal immunity
- PBMCs
- primary immune cells
- epithelial cells
- tissue explants
- Data Science
- multi-omic outputs
- statistical analyses
- Gastroenterology
- Gastrointestinal Disease
- Inflammatory Bowel Diseases
Noch nicht perfekt?
- Novartis Pharma AGVollzeitnur vor OrtBerufserfahrenBasel
- Roche
Senior Scientist - Mucosal Immunology(m/w/x)
Vollzeitnur vor OrtManagementBasel - Institute of Human Biology (IHB)
Post Doctorate Scientist in Intestinal Inflammation(m/w/x)
Vollzeitnur vor OrtSeniorBasel - 1201 F. Hoffmann-La Roche AG
Clinical Scientist immunology(m/w/x)
Vollzeitnur vor OrtSeniorBasel - Roche
Medical Director, Gastroenterology, Early Clinical Development(m/w/x)
Vollzeitnur vor OrtSeniorBasel
Principal Scientist - Translational Intestinal Immunology(m/w/x)
Linking human IBD biology to druggable targets using in vitro human models and biosamples. At least 3 years translational research expertise required. Work in a 15-person R&D team focused on next-gen medicines.
Anforderungen
- PhD or MD in Mucosal Immunology, Gastroenterology, Barrier Immunology, or related field
- At least 3 years translational research expertise in interdisciplinary setting
- Mastery of immunological/cell biology/molecular biology assays
- Mastery of in vitro human models relevant to IBD and mucosal immunity
- Ability to conduct experiments using in vitro human systems and biosamples
- Experience with sample-tracking best practices and consent/ethics
- Collaboration with data scientists
- Ensuring high quality experimental design and reproducibility
- Track record of completing projects on schedule
- Mentoring junior researchers
- Contributing to drug discovery programs
- Experience in translational academic/clinical setting
- Data Science literacy
- Confidence interpreting multi-omic outputs and statistical analyses
- Gastroenterology knowledge
- Gastrointestinal Disease knowledge
- Inflammatory Bowel Diseases knowledge
Aufgaben
- Design and execute mechanistic experiments
- Link human disease biology to druggable targets
- Accelerate preclinical compound development
- Strengthen understanding of drug modes of action
- Differentiate novel drugs from standard-of-care treatments
- Leverage human biosamples for decision-making data
- Position candidate molecules for clinical trials
- Conduct target validation studies
- Perform MoA studies
- Develop biomarker strategies
- Partner with early clinical teams
- Test clinical hypotheses for early clinical strategies
- Champion data-driven target discovery
- Collaborate with data scientists and in vivo biology labs
- Connect quantitative methods to patient heterogeneity
- Drive a culture of collaboration
- Foster talent development
- Maintain integrity in research
Berufserfahrung
- 3 Jahre
Ausbildung
- Doktor / Ph.D.
Sprachen
- Englisch – verhandlungssicher
Tools & Technologien
- multi-parametric flow cytometry
- IBD
- mucosal immunity
- PBMCs
- primary immune cells
- epithelial cells
- tissue explants
- Data Science
- multi-omic outputs
- statistical analyses
- Gastroenterology
- Gastrointestinal Disease
- Inflammatory Bowel Diseases
Über das Unternehmen
Novartis Pharma AG
Branche
Pharmaceuticals
Beschreibung
Das Unternehmen setzt sich für Vielfalt, Chancengleichheit und Inklusion ein und fördert innovative Lösungen zur Verbesserung der Patientenversorgung.
Noch nicht perfekt?
- Novartis Pharma AG
Principal Scientist - Translational Intestinal Immunology(m/w/x)
Vollzeitnur vor OrtBerufserfahrenBasel - Roche
Senior Scientist - Mucosal Immunology(m/w/x)
Vollzeitnur vor OrtManagementBasel - Institute of Human Biology (IHB)
Post Doctorate Scientist in Intestinal Inflammation(m/w/x)
Vollzeitnur vor OrtSeniorBasel - 1201 F. Hoffmann-La Roche AG
Clinical Scientist immunology(m/w/x)
Vollzeitnur vor OrtSeniorBasel - Roche
Medical Director, Gastroenterology, Early Clinical Development(m/w/x)
Vollzeitnur vor OrtSeniorBasel