Dein persönlicher KI-Karriere-Agent
Intern In Vitro Brain Distribution of Biologics(m/w/x)
Generating experimental data for biologics in neurosciences, establishing in vitro assays for antibody uptake and transcytosis. Mammalian cell culture and blood-brain barrier model experience required. Personal expression encouraged, open dialogue fostered.
Anforderungen
- Master’s or PhD program enrollment or degree completed within 12 months of start date, preferably in biochemistry, pharmacology, or molecular biology
- Eagerness to start career in pharmaceutical industry
- Hands-on experience with mammalian cell culture techniques
- Experience with primary or established blood-brain barrier models (e.g., transwell setups)
- Technical skills in cell engineering (plasmid transfection, viral transduction)
- Generation of engineered reporter cell lines
- Execution of fluorescence and luminescence-based in vitro assays
- Basic data analysis and experimental reporting
- Interest in translational science and drug delivery systems
- Fundamental understanding of pharmacokinetics
- Innovative problem-solving skills
- Strong communication skills
- English proficiency
- Ability to work independently with minimal supervision
- Teamwork skills
- Non-EU/Non-EFTA citizens: university confirmation of mandatory internship
- Non-EU/Non-EFTA citizens: continuous enrollment in university or PhD program for internship duration
Aufgaben
- Generate experimental data for biologics in neurosciences
- Establish in vitro assay for antibody uptake and transcytosis
- Study antibody recycling to understand PK properties
- Develop in vitro-in vivo correlation (IVIVC)
- Collaborate in multi-disciplinary team
- Gain hands-on experience with advanced methodologies
- Work with in vitro cellular models and bioluminescence assays
- Conduct transwell assays and microscopy techniques
- Develop and optimize in vitro models like BBB transwell systems
- Support drug development with quantitative kinetic methodologies
- Evaluate real-time cellular target engagement
- Use advanced split-luciferase technology
- Analyse and document experimental results
- Maintain high scientific standards in documentation
Ausbildung
- Abgeschlossene BerufsausbildungODER
- Laufendes Studium
Sprachen
- Englisch – verhandlungssicher
Tools & Technologien
- mammalian cell culture
- transwell setups
- plasmid transfection
- viral transduction
- fluorescence assays
- luminescence assays
Benefits
Lockere Unternehmenskultur
- Personal expression encouraged
- Open dialogue fostered
- Genuine connections valued
- Accepted and respected
Mentoring & Coaching
- Personal and professional thriving
Gefällt dir diese Stelle?
BetaDein Career Agent findet täglich ähnliche Jobs für dich.
Noch nicht perfekt?
- F. Hoffmann-La Roche AGVollzeitPraktikumnur vor OrtBasel
- Roche
M.Sc. Internship - in vitro Human Model Systems(m/w/x)
VollzeitPraktikumnur vor OrtBasel - F. Hoffmann-La Roche AG
RiSE Internship - Targeting CNS Meninges(m/w/x)
VollzeitPraktikumnur vor OrtBasel - F. Hoffmann-La Roche AG
Master Student Internship in Bioanalytics and Biomarkers(m/w/x)
VollzeitPraktikumnur vor OrtBasel - F. Hoffmann-La Roche AG
Student Internship for Engineering, Life & Pharmaceutical Sciences in Pharmaceutical Development(m/w/x)
VollzeitPraktikumnur vor OrtBasel
Intern In Vitro Brain Distribution of Biologics(m/w/x)
Generating experimental data for biologics in neurosciences, establishing in vitro assays for antibody uptake and transcytosis. Mammalian cell culture and blood-brain barrier model experience required. Personal expression encouraged, open dialogue fostered.
Anforderungen
- Master’s or PhD program enrollment or degree completed within 12 months of start date, preferably in biochemistry, pharmacology, or molecular biology
- Eagerness to start career in pharmaceutical industry
- Hands-on experience with mammalian cell culture techniques
- Experience with primary or established blood-brain barrier models (e.g., transwell setups)
- Technical skills in cell engineering (plasmid transfection, viral transduction)
- Generation of engineered reporter cell lines
- Execution of fluorescence and luminescence-based in vitro assays
- Basic data analysis and experimental reporting
- Interest in translational science and drug delivery systems
- Fundamental understanding of pharmacokinetics
- Innovative problem-solving skills
- Strong communication skills
- English proficiency
- Ability to work independently with minimal supervision
- Teamwork skills
- Non-EU/Non-EFTA citizens: university confirmation of mandatory internship
- Non-EU/Non-EFTA citizens: continuous enrollment in university or PhD program for internship duration
Aufgaben
- Generate experimental data for biologics in neurosciences
- Establish in vitro assay for antibody uptake and transcytosis
- Study antibody recycling to understand PK properties
- Develop in vitro-in vivo correlation (IVIVC)
- Collaborate in multi-disciplinary team
- Gain hands-on experience with advanced methodologies
- Work with in vitro cellular models and bioluminescence assays
- Conduct transwell assays and microscopy techniques
- Develop and optimize in vitro models like BBB transwell systems
- Support drug development with quantitative kinetic methodologies
- Evaluate real-time cellular target engagement
- Use advanced split-luciferase technology
- Analyse and document experimental results
- Maintain high scientific standards in documentation
Ausbildung
- Abgeschlossene BerufsausbildungODER
- Laufendes Studium
Sprachen
- Englisch – verhandlungssicher
Tools & Technologien
- mammalian cell culture
- transwell setups
- plasmid transfection
- viral transduction
- fluorescence assays
- luminescence assays
Benefits
Lockere Unternehmenskultur
- Personal expression encouraged
- Open dialogue fostered
- Genuine connections valued
- Accepted and respected
Mentoring & Coaching
- Personal and professional thriving
Gefällt dir diese Stelle?
BetaDein Career Agent findet täglich ähnliche Jobs für dich.
Über das Unternehmen
Roche
Branche
Pharmaceuticals
Beschreibung
The company is dedicated to advancing science and ensuring access to healthcare for everyone.
Noch nicht perfekt?
- F. Hoffmann-La Roche AG
Internship, Multimodal Bioimage Analysis (6-12 months)(m/w/x)
VollzeitPraktikumnur vor OrtBasel - Roche
M.Sc. Internship - in vitro Human Model Systems(m/w/x)
VollzeitPraktikumnur vor OrtBasel - F. Hoffmann-La Roche AG
RiSE Internship - Targeting CNS Meninges(m/w/x)
VollzeitPraktikumnur vor OrtBasel - F. Hoffmann-La Roche AG
Master Student Internship in Bioanalytics and Biomarkers(m/w/x)
VollzeitPraktikumnur vor OrtBasel - F. Hoffmann-La Roche AG
Student Internship for Engineering, Life & Pharmaceutical Sciences in Pharmaceutical Development(m/w/x)
VollzeitPraktikumnur vor OrtBasel