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Senior Scientist - xRNA /sIRNA Discovery(m/w/x)
Developing and validating cell-based assays for xRNA/siRNA discovery, including transfection and qPCR, at a biotech firm. Minimum 3-5 years lab research in pharma/biotech with mammalian cell culture and mRNA/protein isolation experience required. Inclusive work environment, focus on patient care.
Requirements
- MS or Bachelor's/scientific apprenticeship with at least 5 years of industry experience or recent graduate PhD with 0-1 years of industry experience
- Minimum of 3-5 years of laboratory research experience in pharma or biotech industry
- Strong hands-on experience in cell and molecular biology techniques
- Mammalian and primary cell culture
- mRNA and protein isolation, characterization and quantification
- Next-generation sequencing workflows
- Experience with liquid-handling systems and automation of cell-based assays or strong interest in developing such
- Proven ability to troubleshoot and refine assays
- Strong competence in MS Office applications and data analysis software
- Excellent organizational skills and attention to detail
- Ability to collaborate and thrive in a fast-paced, team-oriented research environment
- Familiarity with primary cell culture models
- Exposure to bioinformatics and coding for data processing, visualization and analysis
- Experience with specific automation platforms is a strong plus
Tasks
- Design and execute siRNA screening experiments
- Conduct cell-based transfection assays
- Perform qPCR and reporter-based readouts
- Develop and optimize biochemical assays
- Validate cell-based assays for siRNA discovery
- Contribute to automated workflows with liquid-handling robotics
- Drive improvements in lab organization and workflows
- Implement new technologies and equipment
- Collaborate with an interdisciplinary team
- Present data and conclusions clearly in verbal and written form
- Maintain high-quality records in electronic lab notebooks
- Analyze and report results in a timely manner
Work Experience
- 3 - 5 years
Education
- Bachelor's degree
Languages
- English – Business Fluent
Tools & Technologies
- qPCR
- CLIP
- IP
- ELISA
- Western blot
- NGS library preparation
- BioMek
- Opentrons
- GraphPad Prism
- Spotfire
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Senior Scientist - xRNA /sIRNA Discovery(m/w/x)
Developing and validating cell-based assays for xRNA/siRNA discovery, including transfection and qPCR, at a biotech firm. Minimum 3-5 years lab research in pharma/biotech with mammalian cell culture and mRNA/protein isolation experience required. Inclusive work environment, focus on patient care.
Requirements
- MS or Bachelor's/scientific apprenticeship with at least 5 years of industry experience or recent graduate PhD with 0-1 years of industry experience
- Minimum of 3-5 years of laboratory research experience in pharma or biotech industry
- Strong hands-on experience in cell and molecular biology techniques
- Mammalian and primary cell culture
- mRNA and protein isolation, characterization and quantification
- Next-generation sequencing workflows
- Experience with liquid-handling systems and automation of cell-based assays or strong interest in developing such
- Proven ability to troubleshoot and refine assays
- Strong competence in MS Office applications and data analysis software
- Excellent organizational skills and attention to detail
- Ability to collaborate and thrive in a fast-paced, team-oriented research environment
- Familiarity with primary cell culture models
- Exposure to bioinformatics and coding for data processing, visualization and analysis
- Experience with specific automation platforms is a strong plus
Tasks
- Design and execute siRNA screening experiments
- Conduct cell-based transfection assays
- Perform qPCR and reporter-based readouts
- Develop and optimize biochemical assays
- Validate cell-based assays for siRNA discovery
- Contribute to automated workflows with liquid-handling robotics
- Drive improvements in lab organization and workflows
- Implement new technologies and equipment
- Collaborate with an interdisciplinary team
- Present data and conclusions clearly in verbal and written form
- Maintain high-quality records in electronic lab notebooks
- Analyze and report results in a timely manner
Work Experience
- 3 - 5 years
Education
- Bachelor's degree
Languages
- English – Business Fluent
Tools & Technologies
- qPCR
- CLIP
- IP
- ELISA
- Western blot
- NGS library preparation
- BioMek
- Opentrons
- GraphPad Prism
- Spotfire
Like this job?
BetaYour Career Agent finds similar jobs for you every day.
About the Company
Novartis Pharma AG
Industry
Pharmaceuticals
Description
Das Unternehmen setzt sich für Vielfalt, Chancengleichheit und Inklusion ein und fördert innovative Lösungen zur Verbesserung der Patientenversorgung.
Not a perfect match?
- Novartis Pharma AG
Senior Scientist - xRNA /sIRNA Discovery(m/w/x)
Full-timeOn-siteSeniorBasel - 1201 F. Hoffmann-La Roche AG
RNA Biology Associate(m/w/x)
Full-timeOn-siteExperiencedBasel - Novartis Pharma AG
Senior Scientist – Small Scale Oligonucleotide Synthesis(m/w/x)
Full-timeOn-siteSeniorBasel - Roche
Senior Scientist, Translational Medicine Oncology (Hematology)(m/w/x)
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Principal Scientist, Mid/Large Scale Oligonucleotide Synthesis, xRNA Therapeutics(m/w/x)
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