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OCOctapharma Biopharmaceuticals GmbH

Scientist R&D Molecular Design(m/w/x)

Heidelberg
Full-timeOn-siteExperienced

Designing and screening phage display libraries with NGS workflows for therapeutic discovery at a human protein manufacturer. Ph.D. in Molecular Biology or M.Sc. with 3+ years relevant experience, plus hands-on phage display platforms experience required. 30 days vacation, company restaurant with subsidies, free drinks.

Requirements

  • Ph.D. in Molecular Biology, Biochemistry, Immunology, or related field or M.Sc. with at least 3 years relevant professional experience
  • Hands-on experience with phage display platforms and antibody/peptide selection techniques
  • Strong knowledge of library design and construction, molecular cloning, and expression systems
  • Proficiency in NGS workflows for diversity analysis and hit tracking
  • Excellent scientific research, data analysis, and interpretation skills
  • Excellent communication skills in English; German knowledge is a plus
  • Strong problem-solving ability, attention to detail, and capacity to work independently and collaboratively
  • Understanding of antibody structure-function relationships and engineering strategies
  • Experience with automation and high-throughput screening
  • Programming or scripting experience for data analysis
  • Familiarity with other display technologies

Tasks

  • Design and construct phage display libraries for therapeutic discovery campaigns
  • Perform selection and screening of phage libraries using biopanning and enrichment strategies
  • Integrate Next-Generation Sequencing (NGS) workflows for library quality control and diversity assessment
  • Analyze sequencing and experimental data to monitor enrichment and guide candidate optimization
  • Develop and optimize directed evolution strategies to improve affinity, stability, and developability
  • Collaborate with protein engineering, computational biology, and project teams
  • Coordinate external lead discovery activities
  • Prepare scientific reports and documentation
  • Present findings in project and departmental meetings
  • Stay informed about the latest scientific developments and apply insights to ongoing projects

Work Experience

  • 3 years

Education

  • Master's degree

Languages

  • EnglishBusiness Fluent
  • GermanBasic

Tools & Technologies

  • NGS workflows
  • bioinformatics tools

Benefits

Flexible Working

  • Flexible working hours

Learning & Development

  • Regular opportunities for further training

More Vacation Days

  • 30 days vacation

Free or Subsidized Food

  • Own company restaurant with subsidies

Snacks & Drinks

  • Free drinks
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